211248 Risk factors for occult nodal metastasis in patients with stageⅠA peripheral non－small cell lung cancer

/Jin Luming(金璐明，Dept Thirac Surg，Peop Hosp，Peking Univ，Beijing 100044)…∥Chin J Thorac Cardiovasc Surg.-2011，27(4).-212 ～214

ObjectiveTo study the risk factors of mediastinal lymph node metastasis in patients with≤3 cm peripheral non-small cell lung cancer.MethodsFrom January 2000 to December 2010，a total of 281 patients with NSCLC ［152 men and 129 women，aged(60.31 ±12.13)years;≤ 3 cm in diameter］underwent lobectomy or partial resection with systematic mediastinal lymphadenectomy in hospital.Clinical data included age，gender，symptoms，history and quantity of smoking history，history of tumor，family history of tumor，site，diameter，calcification，speculation，border，lobulation，traction of pleural，vascular convergence sign，cavity were collected compaired and analyzed.Single and multi-variate analysis was performed to determine the independent risk of occult N2 nodal involvement.ResultsLogistic regression analysis showes seven clinical characteristics(fleshless(OR:22.262)，history of tumor(OR:5.485)，diameter(0R:3.788)，density(OR;5.850)，traction of pleural(OR:1.371)，border(OR:8.259)and cavity(OR:7.124)were risk factors.ConclusionFleshless，history of tumor，diameter，density，traction of pleural and the border and cavity were independent predictors of malignancy in patients with≤3 cm peripheral non-small cell lung cancer.13 refs，2 tabs.