Evaluation on short term after hepatectomy for the patients with primary hepatocellular carcinoma

/Wu Liqun

(吳力群，Dept Hepatobil Surg，Affil Hosp Med Col Qingdao Univ，Qingdao 266003)…∥Chin J Surg.-2011，49(9).-784～788

ObjectiveTo analyze the high risk factors for tumor recurrence in short term after hepatectomy for the patients for the patients with primary hepatocellular carcinoma(HCC).MethodsFive hundreds and two patients with primary HCC underwent hepatectomy were included from Jannary 1997 to Ddeccoember 2008.Among these patients，males were 419 cases and females were 83 cases.The age was 14 to 82 years(average age 54 years).The results of evaluation on 2 months after resection and tumor recurrence and survival were analyzed.ResultsAccording to the operative and pathologic and the evaluation on 2 months after hepatectomy，the patients with vascular invasion，palliation resection，cutting edge pathologic residual tumor，lymph notes metastasis，serum AFP level continuing higher after resection or(and)positive TACE(tumordyeing on TACE within 1 months and deposit of lipiodol on CTscan)were high risk factors(high-risk group，106 cases，21.1%)，the recurrence-free survival was 22%，9%and 3%(1，2 and 5 years)and overall survival was 52%，25%and 8%.On the non-high risk group patients，the recurence-free survival was 84%，67%，42%and 31%(1，2，and 5 years)and overall survival was 97% ，85% ，56%and 35% .The bigger tumor，poor differeniation，tumor invading to liver capsule，satellite focus and TNM Ⅲ-Ⅳ stage in high-risk group were more significantly than that in non-high-risk group.ConclusionThe vascular invasion，palliation resection，cutting edge pathologic residual tumor，lymph notes metastasis，serum AFP level continuing higher or(and)positive TACE within 2 months after resection are high risk factors for HCC patients in short term after hepatectomy，which mean tumor remnant.8 refs，2 figs ，3 tabs