Endovascular treatment for severe Takayasu’s arteritis

/Jiang Hong

(姜宏，Dept Radiol Interven，Gen Hosp Shenyang Mil Command，Shenyang 110840)…∥Chin J Gen Surg.-2011，26(10).-841～844

ObjectiveTo evalute the clinical application of endovascular treatment for severe Takayasu’s artertis(TA).MethodsIn this study，35 target lesions in 32 patients［28 women，mean age(30 ± 8)years］with severe Takayasu’s arteritis were treated with endovascular method.The average length of lesion was 3.1 cm(range 2.7-5.3).The overall average degree of diameter stenosis was 90%±11%(range 70-100)in which 15 lesions were completely occlusive.There were 10 patients whose ESR were higher than 20 mm/h(range 25-37).Follow-up included physical examination and patency evaluated by color duplex sonography/computed tomography angiography/angiography at 6 months and then annually.ResultsRecanlization was unsuccessful in 3 completely occlusive lesions，with a successful rate of 80%(12/15).There was one case in which embolization leading to acute thrombogenesis developed during interventional procedure and resulting in severe stroke.The technical successful rate(residual stenosis＜50%)was 88.6%(31/35).The transient cerebral ischemia attack(TIA)symptoms disappeared in 31 cases.26 cases were followed up for an average of(19±10)months later in one case.Symptomatic in-stent restenosis 18 months later was found in 2 cases.Patency rate was 88.5%(23/26).ConclusionEndovascular treatment is safe and effective for severe TA.Strict indication and accurate targeting the lesions help ensure the success of management.11refs，2 figs