

[摘要] 目的 探討超早期急性腦梗死應用阿替普酶靜脈溶栓治療的臨床療效。方法 隨機選取2014年9月—2016年6月該院收治的50例急性腦梗死患者為研究對象,全部患者均用藥阿替普酶進行超早期急診救治。依救治時間不同將入選病例分為2組:實驗組25例,患者發病3 h內用藥;對照組25例,患者發病3~6 h用藥,對比分析兩組用藥療效。結果兩組均無死亡病例,救治成功率100%;實驗組患者治療后NIHSS改善效果優于對照組(P<0.05),治療總有效率(96.0%)與對照組(92.0%)相比差異無統計學意義(P>0.05)。兩組治療后凝血功能各項指標均差異無統計學意義(P>0.05)。結論 以阿替普酶對急性腦梗死患者進行超早期溶栓治療可有效改善患者神經功能缺損癥狀,應用療效顯著,安全性良好,值得推廣使用。
[關鍵詞] 急性腦梗死;超早期治療;阿替普酶;靜脈溶栓
[中圖分類號] R743 [文獻標識碼] A [文章編號] 1674-0742(2016)10(b)-0132-03
[Abstract] Objective To investigate the clinical efficacy of intravenous thrombolytic therapy for acute cerebral infarction in patients with super early stage of cerebral infarction. Methods Random selection 50 cases of patients with acute cerebral infarction treated in our hospital from September 2014 — June 2016 as the research object, all the patients were treated with the drug. According to the treatment time, the selected cases were divided into 2 groups: the experimental group 25 cases, the incidence of 3H in patients with medication; the control group of 25 cases, the incidence of 3~6 h drug use, comparative analysis of the two groups of drug efficacy. Results The two groups had no death cases, treatment success rate of 100%; after treatment, the patients in the experimental group nhiss effect is better than that of control group (P < 0.05), the treatment efficiency (96.0%) and control group (92.0%) showed no significant difference (P > 0.05). There was no statistical difference in coagulation function after treatment in the two groups (P > 0.05).Conclusion Super early thrombolytic therapy for acute cerebral infarction can effectively improve the neurological function of patients with acute cerebral infarction. It has a good curative effect and good safety, and it is worth popularizing.
[Key words] Acute cerebral infarction; Super early treatment; Intravenous thrombolytic therapy; Intravenous thrombolysis
急性腦梗死是指動脈狹窄或堵塞導致腦供血不足所引起的腦組織壞死,其發病機制復雜,高致病風險因素多[1]。臨床研究發現,急性腦梗死超早期治療可有效降低患者死亡風險,對改善患者預后具有重要意義。該院近年來以阿替普酶靜脈溶栓予以急性腦梗死患者超早期治療取得良好臨床效果,文章現以2014年9月—2016年6月該院收治的50例急性腦梗死患者為例,對此進行深入分析和探討,現報道如下。
1 資料與方法
1.1 一般資料
隨機選取該院收治的50例急性腦梗死患者為研究對象,全部患者經臨床診斷,病癥均符合《中國腦血管病防治指南》中關于本病的相關診斷標準[2]?!?br>