

摘要:目的 探討特發性黃斑視網膜前膜的相關因素,對特發性黃斑視網膜前膜的預防以及早期診斷提供臨床指導。方法 選取我院2014年4月~2016年4月收治的經我院確診為特發性黃斑視網膜前膜單眼發病的患者101例(101眼),作為觀察組。另選取于我院就診的無黃斑區病變的其他患者101 例(101眼) 作為對照組,對其進行回顧性病例分析,研究特發性黃斑視網膜前膜的相關因素。結果 單因素及多因素分析顯示,2型糖尿病和高LDL有統計學意義(P<0.05)。結論 糖尿病和高脂血癥是特發性黃斑前膜的相關因素。
關鍵詞:特發性黃斑視網膜前膜;糖尿病;高脂血癥
Analysis of Predisposing Factors of Idiopathic Macular Epiretinal Membrane
SUN Jing1,HE Ping2
(1.Hospital of Renmin University, Beijing 100872, China;2.The Third Affiliated Hospital of Beijing University of Chinese Medicine,Beijing 100013,China)
Abstract:Objective To explore the predisposing factors of idiopathic macular epiretinal membrane, and provide clinical guidance for prevention and early diagnosis of idiopathic macular epiretinal membrane. Methods Clinical data about 101 patients (101 eyes) with idiopathic macular epiretinal membrane admitted to our hospital from April 2014 to April 2016 were retrospectively analyzed.The 101 eyes with idiopathic macular epiretinal membrane were served as the observation group and the normal eyes (n=101) of the 101 patients were served as the function control group. Another 101 patients (101 eyes) without idiopathic macular epiretinal membrane who admitted to our hospital were served as the control group.Results The results factor and multiple factors analysis shows DM(2) and high LDL obvious correlation between the related factors of IMEM recurrence。Conclusion Diabetes and hyperlipidaemia are the predisposing factors of idiopathic macular epiretinal membrane.
Key words:Idiopathic macular epiretinal membrane;Diabetes mellitus;Hyperlipidaemia
黃斑視網膜前膜(macular epiretinal membrane):指在黃斑區視網膜內表面生長的纖維無血管的細胞性增殖膜,類似的病名還有:視網膜前纖維增生癥(preretinal fibrosis),黃斑皺縮綜合癥(macular pickling syndrome),玻璃紙樣黃斑病變(cellophane maculopathy)及黃斑皺褶(macular pucker)等,是影響視力的一個重要原因,尤其是老年人。大部分患者的黃斑視網膜前膜形成的原因不明,稱為特發性黃斑視網膜前膜(idiopathyic macular epiretinal membrane),臨床上以排除繼發性黃斑視網膜前膜因素后確診[1]。患者早期可無典型臨床表現,隨著病情的發展,出現視力下降、視物變小、視物變形和單眼復視。特發性黃斑視網膜前膜發病年齡在55~75歲,偶見青年人。20%左右患者雙眼發病,但多數雙眼發病患者雙眼病變程度不同[2]。近年來,IMEM的發病率逐漸升高,成為損害中老年人視功能的重要因素[3-4]。本研究對我院收治的101例IMEM患者的臨床資料進行回顧分析,探討該病的易感因素,對預防以及早期診斷提供臨床指導。……