王美芳

[摘要] 目的 通過對呼吸內科患者實施不同的臨床干預,觀察不同干預方法的臨床效果,探究不同臨床干預的臨床特點。 方法 2018年1—10月間從來該院診治的呼吸內科患者中隨機抽取55例,采用隨機數字法隨機分為對照組28例:實施常規抗生素治療,觀察組27例:實施臨床藥學干預,比較兩組的抗生素使用及住院時間情況、不良反應發生率、病原學檢測率及三聯以上抗生素使用率。 結果 觀察組住院時間為(7.61±1.53)d低于對照組(t=14.241,P<0.05),抗生素療程為(5.39±1.81)d低于對照組(t=11.641,P<0.05),抗生素費用為(755.82±14.62)元低于對照組(t=12.482,P<0.05);觀察組不良反應發生率11.11%低于對照組(χ2=8.428, P<0.05),病原學檢測率為14.81%低于對照組(χ2=7.982, P<0.05),三聯以上抗生素使用率為7.41%低于對照組(χ2=9.742, P<0.05),差異有統計學意義(P<0.05)。 結論 臨床藥學干預可以有效降低呼吸內科的住院時間、抗生素療程、抗生素費用,減少不良反應、病原學檢測及三聯以上抗生素使用情況,是一項值得推廣的臨床干預。
[關鍵詞] 臨床藥學干預;呼吸內科;抗生素
[中圖分類號] R95 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1674-0742(2019)04(b)-0127-03
[Abstract] Objective To observe the clinical effects of different intervention methods by different clinical interventions in patients with respiratory medicine, and to explore the clinical characteristics of different clinical interventions. Methods A total of 55 patients with respiratory medicine from January 2018 to October 2018 in our hospital were randomly selected and randomly divided into control group (n=28): routine antibiotic treatment, observation group: 27 cases: clinical pharmacy Interventions were used to compare antibiotic use and length of hospital stay, incidence of adverse events, etiology, and antibiotic use rates above the triple. Results The hospitalization time of the observation group was (7.61±1.53)d lower than that of the control group (t=14.241, P<0.05), the antibiotic course was (5.39±1.81)d lower than the control group (t=11.641, P<0.05), and the antibiotic cost was (755.82±14.62)yuan was lower than the control group (t=12.482, P<0.05); the incidence of adverse reactions in the observation group was 11.11% lower than that in the control group (χ2=8.428, P<0.05), and the pathogen detection rate was 14.81% lower than the control group (χ2=7.982, P<0.05), the use rate of triple antibiotics was 7.41% lower than that of the control group (χ2=9.742, P<0.05),the different was statistically significant(P<0.05). Conclusion ?Clinical pharmacological intervention can effectively reduce the hospitalization time, antibiotic course, antibiotics of respiratory medicine cost, reducing adverse reactions, pathogen detection and the use of antibiotics above the triple is a clinical intervention worthy of promotion.
[Key words] Clinical pharmacy intervention; Respiratory medicine; Antibiotics
呼吸內科比較常見的疾病有慢性支氣管炎、支氣管哮喘、支氣管擴張、慢性阻塞性肺氣腫、肺炎以及呼吸衰竭等。近年,隨著空氣污染加重,呼吸內科患者發病率呈上升趨勢,臨床常用藥物為抗生素,但是,長期大量的不合理使用抗生素容易提高患者耐藥性,影響抗生素治療效果[1]。呼吸內科各種疾病具有不同程度炎癥反應,針對此類情況臨床給予不同抗生素預防和治療[2]。多種抗生素的使用嚴重危害人們的生活和健康[3]。從來該院診治的2018年1—10月的呼吸內科患者中隨機抽取55例,采用隨機數字法隨機分為對照組和觀察組,分別實施常規抗生素和臨床藥學干預治療,獲得臨床效果差異顯著,現報道如下。
1 ?資料與方法
1.1 ?一般資料
從來該院診治的呼吸內科患者中隨機抽取55例,男性30例,女性25例,年齡范圍45~80歲,平均年齡為(46.75±8.27)歲。采用隨機數字法隨機分為對照組28例……