宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕臨床研究

丁嬌 邵軍暉 楊琳

摘 要 目的：探討宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕的臨床療效。方法：將2015年12月至2017年12月接診的輸卵管性不孕患者60例隨機分為觀察組和對照組各30例。對照組采用宮腹腔鏡手術治療，觀察組在對照組治療的基礎上聯合輔助生殖技術治療。觀察患者輸卵管梗阻、再疏通、并發癥發生及妊娠情況。結果：兩組輸卵管梗阻、再疏通及并發癥發生率差異無統計學意義（P>0.05）。觀察組1年妊娠19例（63.33%），2年妊娠25例（83.33%），對照組分別為11例（36.67%）和17例（56.67%），組間差異有統計學意義（P<0.05）。結論：宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕對患者的輸卵管梗阻及再疏通情況影響較小，未增加患者的并發癥發生情況，但患者的1、2年妊娠率明顯提高，應用價值較高。

關鍵詞 輸卵管性不孕；宮腹腔鏡；輔助生殖技術

中圖分類號：R711.6 文獻標志碼：A 文章編號：1006-1533（2019）06-0022-02

Clinical study of hysteroscopy-laparoscopy combined with assisted reproductive technology in the treatment of tubal infertility

DING Jiao， SHAO Junhui， YANG Lin（Assisted Reproductive Department of Maternal and Child Health Care Center of Xinyu， Xinyu 338000， Jiangxi Province， China）

ABSTRACT Objective： To explore the clinical efficacy of hysteroscopy-laparoscopy combined with assisted reproductive technology in the treatment of tubal infertility. Methods： Sixty patients with tubal infertility who were admitted from December 2015 to December 2017 were randomly divided into an observation group and a control group with 30 cases in each group. The control group was treated with laparoscopic surgery， and the observation group was combined with assisted reproductive technology treatment based on the treatment of the control group. The patients fallopian tube obstruction， recanalization， complications and pregnancy were observed. Results： There were no significant differences in the incidence of tubal obstruction， recanalization and complication between the two groups（P>0.05）. In the observation group， 19 cases（63.33%） were pregnant in 1 year， 25 cases（83.33%） in 2 years of pregnancy， and in the control group， 11 cases（36.67%） and 17 cases（56.67%）， and the difference between the groups was statistically significant（P<0.05）. Conclusion： Hysteroscopy-laparoscopy combined with assisted reproductive technology in the treatment of tubal infertility has less influence on the tubal obstruction and recanalization， and do not increase the patients complications， but the pregnancy rate of the patients is significantly improved in 1 and 2 years， and the application value is higher.

KEY WORDS tubal infertility； hysteroscopy-laparoscopy； assisted reproductive technology

輸卵管性不孕癥影響夫妻和諧、家庭幸福。輸卵管具有運送精子、拾取卵子及把受精卵運送到子宮腔的重要作用，輸卵管不通或功能障礙是造成女性不孕癥的主要原因[1-2]。造成輸卵管不通或功能障礙的原因是急、慢性輸卵管炎癥。隨著微創技術的發展，宮腹腔鏡技術不斷成熟，并在婦科廣泛應用[3-4]。采用宮腹腔鏡治療創傷小、術后易恢復，優勢明顯[5]。本文報道采用宮腹腔鏡聯合輔助生殖技術治療輸卵管性不孕的療效。

1 資料與方法

1.1 一般資料