
DOI:10.16662/j.cnki.1674-0742.2016.32.049
[摘要] 目的 探討亞低溫聯合開顱去骨瓣減壓術對顱腦損傷后急性腦腫脹(TACS)的治療效果。方法 隨機選擇2013年1月—2016年1月該院收治的TACS患者100例,將其均分為研究組與對照組。對照組行開顱去骨瓣減壓術療,研究組在此基礎上應用亞低溫治療。結果 兩組死亡率比較中,研究組36.0%低于對照組56.0%(P<0.05);兩組恢復良好比較中,研究組30.0%高于12.0%(P<0.05)。結論 亞低溫聯合開顱去骨瓣減壓術治療TACS療效可靠,適于臨床應用。
[關鍵詞] 亞低溫;開顱去骨瓣減壓術;顱腦損傷;急性腦腫脹
[中圖分類號] R5 [文獻標識碼] A [文章編號] 1674-0742(2016)11(b)-0049-03
Treatment of Acute Brain Swelling after Traumatic Brain Injury with Mild Hypothermia Combined with Bone Flap Decompression
WANG Ye-ji
Department of Neurosurgery, Central Hospital of Shanxian County, Shandong Province, Shanxian, Shandong Province, 274300 China
[Abstract] Objective To investigate the therapeutic effect of mild hypothermia combined with bone flap decompression on acute brain swelling (TACS) after traumatic brain injury. Methods Random selection 100 cases of TACS in our hospital from January 2013 to January 2016 were divided into study group and control group, cases were divided into two groups. In the control group, the treatment of bone flap decompression was performed, and the study group was treated with mild hypothermia. Results In comparison of the two groups, the study group was 36% lower than that of the control group 56%(P<0.05); the two groups recovered well, and the study group was 30% higher than 12% (P<0.05). Conclusion Mild hypothermia combined with bone flap decompression in the treatment of TACS is reliable, and it is suitable for clinical application.
[Key words] Mild hypothermia; Craniotomy; Brain injury; Acute brain swelling
急性腦腫脹是顱腦損傷后常見的并發癥,具有病情危重、死亡率高等特點。有研究顯示,顱腦損傷后急性腦腫脹(TACS)的死亡率高達80%以上[1]。目前,TACS主要采取保守治療與外科手術治療,然而由于缺少統一的治療方案,臨床收效卻參差不齊。2014年1月—2016年1月,該院對50例TACS患者應用了亞低溫聯合開顱去骨瓣減壓治療,收效滿意,現報道如下。
1 資料與方法
1.1 一般資料
病例資料來自于隨機選取該院住院部收治的TACS患者,共計100例。入組標準:符合顱腦損傷相關診斷標準[2];具有外科開顱去骨瓣減壓術指征;格拉斯哥昏迷量表(GCS)[3]分值在8分及以下;患者家屬對該次研究知情。排除標準:合并其他嚴重臟器及軀體損傷。以隨機數字表將100例患者均分為對照組與研究組各50例。研究組:男30例,女20例;年齡18~70歲,平均(45.6±5.3)歲;致傷原因:交通傷30例,摔跌傷15例,擊打傷5例;受傷-入院時間:0.5~6 h,平均(1.2±0.5)h。對照組:男29例,女21例;年齡18~70歲,平均(45.5±5.3)歲;致傷原因:交通傷29例,摔跌傷16例,擊打傷5例;……