右美托咪定聯合丙泊酚麻醉在老年無痛胃鏡麻醉中的應用效果

連志鵬 張銓

[摘要]目的 對比分析老年無痛胃鏡麻醉中單純應用丙泊酚與其聯合右美托咪定的臨床效果。方法 將我院2016年3月～2017年9月接受無痛胃鏡檢查的88例老年患者作為觀察對象，依照硬幣法分為對照組（n=44）和觀察組（n=44）。對照組患者予以丙泊酚麻醉，觀察組患者予以丙泊酚聯合右美托咪定麻醉，對兩組患者麻醉誘導時間、蘇醒時間、檢查中并發癥及檢查后不良反應發生情況予以統計比較。結果 觀察組患者麻醉誘導時間、蘇醒時間短于對照組，分別為（133.8±19.4）s vs.（147.7±20.6）s、（95.2±16.2）s vs.（116.5±22.4）s，差異有統計學意義（P<0.05）。觀察組患者并發癥發生率低于對照組，分別為4.5%、18.2%，兩組差異有統計學意義（P<0.05）。觀察組患者不良反應發生率為4.5%，與對照組患者（11.4%）比較，差異無統計學意義（P>0.05）。結論 老年無痛胃鏡麻醉應用丙泊酚聯合右美托咪定的效果更加顯著，不僅可縮短麻醉誘導時間與蘇醒時間，還可減少并發癥的發生，具有安全、可靠的特點，值得在臨床中與推廣與應用。

[關鍵詞]無痛胃鏡；丙泊酚；右美托咪定；麻醉

[中圖分類號] R614 [文獻標識碼] A [文章編號] 1674-4721（2018）4（c）-0070-03

Effect of Dexmetomidine combined with Propofol anesthesia on senile painless gastroscopy

LIAN Zhi-peng ZHANG Quan

Department of Anesthesiology，95th Hospital of PLA，Fujian Province，Putian 351200，China

[Abstract]Objective To compare the clinical effect of gastroscopy anesthesia in the elderly treated with Propofol combined with Dexmedetomidine.Methods A total of 88 elderly patients who received painless gastroscopy during the period from March 2016 to September 2017 were selected as observation subjects，and they were divided into control group（n=44） and observation group（n=44） according to the coin method.The control group patients were given Propofol anesthesia，the observation group patients were given Propofol combined Dexmetomidine on anesthesia，two groups of patients anesthesia induction time，recovery time，check the complications and adverse reactions after the test were compared.Results The observation group of patients anesthesia induction time，wake up of time was shorter than that in the control group patients，data respectively（133.8±19.4） s vs.（147.7±20.6） s，（95.2±16.2） s vs. （116.5±22.4） s，the two groups was statistically difference（P<0.05）.The incidence of complications in the observation group was lower than that in the control group，and the data were 4.5% and 18.2%，respectively，and the comparison of the two groups was statistically significant（P<0.05）.The incidence of adverse reactions in the observation group was 4.5%，compared with 11.4% in the control group，no statistical difference（P>0.05）.Conclusion The effect of Propofol combined with Dexmedetomidine in elderly patients with painless gastroscopy anesthesia is more significant，not only can shorten the induction time and recovery time of anesthesia，but also can reduce the occurrence of complications，with safe and reliable features，it is worth in the clinical further application and promotion.