復方聚乙二醇電解質散不同給藥方式對便秘患者腸道準備清潔效果的影響

廖錦文 龍文秀 吳蘭

[摘要] 目的 探討復方聚乙二醇電解質散（SF-PEG）不同給藥方式對便秘患者腸道準備清潔效果的臨床價值。 方法 選取我院消化內鏡室2017年8月～2018年12月擬行無痛結腸鏡檢查的便秘患者144例，隨機分為A、B、C三組，每組48例。A組患者檢查當日一次性口服SF-PEG 2盒溶液2000 mL，B組患者檢查前一天晚上及檢查當日各口服SF-PEG 1盒溶液1000 mL，C組患者在A組的基礎上從服藥開始立即順時針按摩腹部直至勻速把藥液喝完。對比三組患者腸道準備清潔效果、發生不良反應例數、睡眠干擾情況及重復檢查意愿。 結果 三組患者均順利完成無痛結腸鏡檢查。B組和C組患者的腸道準備清潔效果均優于A組（P<0.05）。B組和C組患者發生不良反應的例數明顯低于A組（P<0.05）。A組和C組患者對睡眠影響的例數明顯低于B組（P<0.05）。C組患者重復檢查意愿明顯高于A組和B組（P<0.05）。 結論 SF-PEG結合腹部按摩對便秘患者腸道準備，能獲得良好的腸道清潔效果，不良反應發生率低，且患者睡眠干擾小、重復檢查意愿高，方法簡便易行。

[關鍵詞] 腹部按摩;復方聚乙二醇電解質散;腸道準備;結腸鏡檢查;便秘

[中圖分類號] R574.62 ? ? ? ? ?[文獻標識碼] B ? ? ? ? ?[文章編號] 1673-9701（2020）12-0094-04

[Abstract] Objective To explore the clinical value of different administration methods of compound polyethylene glycol electrolyte powder（SF-PEG） on the cleansing effect of bowel preparation in patients with constipation. Methods A total of 144 patients with constipation who scheduled to undergo painless colonoscopy from August 2017 to December 2018 in our hospital's digestive endoscopy room were randomly divided into three groups： group A， B and C， with 48 cases in each group. Group A was orally given 2 boxes of 2 000 mL of SF-PEG solution on the day of the test， group B was respectively given one box of 1 000 mL of SF-PEG solution on the night before and on the day of the test， and group C was given clockwise abdominal massage from the beginning of taking medicine until the drink was finished on the basis of the group A. The effect of bowel preparation cleaning， the number of adverse reactions， the number of sleep disorders， and the willingness to repeat the test were compared between the three groups. Results All three groups successfully completed painless colonoscopy. The cleansing effect of bowel preparation in group B and C was better than that in group A（P<0.05）. The number of adverse reactions in groups B and C was significantly lower than that in group A（P<0.05）. The number of patients with sleep disorder in group A and C was significantly lower than that in group B（P<0.05）. The willingness in group C to repeat the examination was significantly higher than that in groups A and B（P<0.05）. Conclusion SF-PEG combined with abdominal massage can achieve a remarkable effect on bowel preparation in patients with constipation. It features low incidence of adverse reactions， less interference in sleep， high willingness to repeat tests， and ease of use.

[Key words] Abdominal massage; Compound polyethylene glycol electrolyte powder; Bowel preparation; Colonoscopy; Constipation

電子結腸鏡檢查是目前診斷和篩查結直腸病變最可靠的方法，而良好的腸道準備是完成電子結腸鏡檢查的必備條件[1]。慢性便秘的患者常常因腸道運動異常，導致腸道準備清潔效果較差;而腸道準備不充分可大大地降低電子結腸鏡檢查的質量，增加腸道病變的漏診率。我國專家共識意見推薦2～3 L的復方聚乙二醇電解質散（Compound polyethylene glycol electrolytes powder，SF-PEG）溶液作為常規腸道準備清潔方案[2]。……