中藥足浴治療糖尿病合并冠心病患者的療效及對APN、MBP、IGF-1的影響

范鳳娟 張征宇

[摘要] 目的 分析中藥足浴治療糖尿病合并冠心病患者的療效及對APN、MBP、IGF-1的影響。 方法 選2018年2月至2020年2月間我院內分泌科收治的82例糖尿病合并冠心病患者作為研究對象，均分為兩組（隨機信封法），對照組41例選用常規治療，觀察組41例在對照組基礎上選用中藥足浴治療，統計兩組臨床總有效率、臨床指標、臨床癥狀積分。 結果 觀察組臨床總有效率（92.68%）高于對照組（75.61%），差異有統計學意義（χ2=4.479，P<0.05）。觀察組APN（8.91±1.82）mg/mL、IGF-1（4.94±0.91）pg/mL高于對照組APN（7.52±1.24）mg/mL、IGF-1（4.02±0.52）pg/mL，MBP（8.31±1.62）μg/mL、FPG（5.84±0.42）mmol/L低于對照組MBP（10.62±1.81）μg/mL、FPG（7.52±0.92）mmol/L，差異有統計學意義（P<0.05）。 觀察組臨床癥狀積分低于對照組，差異有統計學意義（P<0.05）。 結論 將中藥足浴應用在糖尿病合并冠心病患者治療中，可降低臨床癥狀積分，改善臨床指標，促進糖脂代謝，值得借鑒。

[關鍵詞] 中藥足浴;糖尿病;冠心病;APN;MBP;IGF-1

[中圖分類號] R259? ? ? ? ? [文獻標識碼] B? ? ? ? ? [文章編號] 1673-9701（2021）25-0140-03

Efficacy of traditional Chinese medicine foot bath in the treatment of patients with diabetes and coronary heart disease and the influence on APN， MBP， and IGF-1

FAN Fengjuan? ?ZHANG Zhengyu

Fifth Ward， Lishui Chinese Medicine Hospital， Zhejiang Province， Lishui? ?323000， China

[Abstract] Objective To analyze the efficacy of traditional Chinese medicine foot bath in treating diabetic patients with coronary heart disease and the influence on APN， MBP， and IGF-1. Methods A total of 82 patients with diabetes and coronary heart disease admitted to the Department of Endocrinology in our hospital from February 2018 to February 2020 were selected as the research subjects. They were divided into two groups （random envelope method）. Forty-one cases in the control group received conventional treatment， and 41 cases in the observation group received the traditional Chinese medicine foot bath based on the treatment of the control group. The total clinical effective rate， clinical indicators， and clinical symptoms scores of the two groups were counted. Results The total clinical effective rate （92.68%） of the observation group was higher than that of the control group （75.61%），the difference was significant（χ2=4.479， P<0.05）. The APN（8.91±1.82） mg/ml， IGF-1（4.94±0.91） pg/mL of the observation group were higher than APN （7.52±1.24） mg/ml， IGF-1 （4.02±0.52） pg/mL of the control group. The MBP （8.31±1.62） μg/ml and FPG （5.84±0.42） mmol/L of the observation group were lower than MBP （10.62±1.81） μg/mL， FPG（7.52±0.92） mmol/L of the control group（P<0.05）. The clinical symptom score of the observation group was lower than that of the control group（P<0.05）. Conclusion The application of traditional Chinese medicine foot bath in the treatment of patients with diabetes and coronary heart disease can reduce clinical symptom scores， improve clinical indicators， and promote glucose and lipid metabolism， which is worth learning.