
[摘要] 目的 研究多廿烷醇和阿托伐他汀聯(lián)用在心血管疾病患者調脂治療方面的療程效果。方法 方便選取該院2015年1月—2016年1月收治的58例心血管疾病患者,將其隨機分為實驗組與對照組,對照組采用阿托伐他汀進行治療,實驗組加用多廿烷醇進行調脂治療,對比兩組患者治療后的調脂治療效果。結果 實驗組治療有效28例,有效率96.55%,不良反應發(fā)生率6.90%,對照組治療有效25例,有效率為86.21%,不良反應發(fā)生率24.14%,差異有統(tǒng)計學意義(P<0.05)。結論 心血管疾病患者的主要發(fā)病原因為血脂異常,因此降低血脂的臨床治療意義重大,對患者采用多廿烷醇和阿托伐他汀聯(lián)用聯(lián)合用藥調脂效果顯著,值得推廣。
[關鍵詞] 心血管疾病;血脂偏高;多廿烷醇;阿托伐他汀聯(lián)用;調脂作用
[中圖分類號] R5 [文獻標識碼] A [文章編號] 1674-0742(2016)12(c)-00102-03
[Abstract] Objective To study the effects of policosanol and atorvastatin in the treatment of cardiovascular disease in patients with lipid-lowering treatment effect. Methods Convenient selection our hospital from January 2015 to January 2016 were 58 cases of patients with cardiovascular disease were randomly divided into experimental group and control group, control group with atorvastatin treatment, experimental group and lipid lowering therapy with policosanol, lipid-lowering treatment effects were compared between the two groups after treatment. Results The experimental group treatment effective in 28 cases, efficiency of 96.55%, the adverse reaction rate was 6.90%, control group 25 cases were effective, effective rate was 86.21%, the adverse reaction rate was 24.14%, the difference was statistically significant(P<0.05). Conclusion The main causes of cardiovascular disease in patients with dyslipidemia, thus reducing the clinical significance of blood lipid is significant, for patients with policosanol and atorvastatin combination lipid-lowering effect is significant, worthy of promotion.
[Key words] Cardiovascular disease; Hyperlipidemia; Policosanol;Atorvastatin; Lipid metabolism
高血脂在我國臨床上的發(fā)病率極大升高,與患者日常生活、飲食習慣有關,且我國老齡化加劇,使得高血脂以及相關疾病的發(fā)病率提高,臨床研究證實,冠心病、高血壓等心血管疾病的主要發(fā)病原因,與患者同時患有高血脂有關,臨床多采用他汀類藥物進行調脂治療,但具有一定的局限性[1]。多廿烷醇由古巴臨床研究分發(fā)現(xiàn)并投入到臨床應用當中,由甘蔗蠟當中提取,其中的脂肪醇含量較為穩(wěn)定,通過食用多廿烷醇,能夠抑制人體中膽固醇的生成,并且?guī)椭颊咛岣唧w內低密度脂蛋白膽固醇的含量,達到降低患者膽固醇、調節(jié)患者血脂的目的,是目前臨床上常用調脂藥物[2-3]。……