
[摘要] 目的 探討滿(mǎn)寶珍元治療高血脂,高血壓合并冠心病的臨床療效。方法 方便收集2013年2月—2015年8月長(zhǎng)春醫(yī)科醫(yī)院高血脂、高血壓合并冠心病的200例患者,分為100例研究組和100例對(duì)照組。對(duì)照組采取降壓、降脂、降低血小板凝聚、營(yíng)養(yǎng)心肌,研究組單純采取滿(mǎn)寶珍元治療。對(duì)比①兩組治療前、治療后心功能分級(jí);②兩組高血壓治療前后水平;③兩組治療期前后血脂水平;④兩組復(fù)發(fā)率及治愈率對(duì)比。 結(jié)果 ①兩組治療前收縮壓、舒張壓分別為(155.4±14.9)mmHg、(94.2±7.5)mmHg和(156.1±15.1)mmHg、(92.1±6.7)mmHg,比較差異無(wú)統(tǒng)計(jì)意義(P>0.05);兩組治療后高血壓水平分別為(135.4±9.2)mmHg、(82.4±5.6)mmHg和(134.1±8.5)mmHg、(86.7±4.2)mmHg,比較差異有統(tǒng)計(jì)意義(P<0.05)。②研究組和對(duì)照組治療前Ch、TG、LDL-C、BMI分別為(5.78±0.38)mmol/L、(2.54±0.36)mmol/L、(2.64±0.27)mmol/L、(25.46±1.21)kg/m2和(5.69±0.31)mmol/L、(2.56±0.38)mmol/L、(2.65±0.31)mmol/L、(25.49±1.35)kg/m2,差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05),研究組和對(duì)照組治療后Ch、TG、LDL-C、HDL-C分別為(5.24±0.24)mmol/L、(2.37±0.28)mmol/L、(2.36±0.19)mmol/L、(24.69±1.18)kg/m2和(5.53±0.47)mmol/L、(2.49±0.35)mmol/L、(2.51±0.22)mmol/L、(25.31±1.28)kg/m2差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。③研究組和對(duì)照組治愈率及復(fù)發(fā)率分別為(100%、0%)、(81%、18%),比較差異有統(tǒng)計(jì)意義(P<0.05)。結(jié)論 滿(mǎn)寶珍元單一用藥比常規(guī)用藥治療高血脂,高血壓合并冠心病療效顯著,應(yīng)作為高血脂,高血壓合并冠心病的首選治療方法。
[關(guān)鍵詞] 滿(mǎn)寶珍元;高血脂;高血壓;冠心病
[中圖分類(lèi)號(hào)] R5 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-0742(2016)12(c)-0001-03
[Abstract] Objective To investigate the treatment of high blood cholesterol with Manbaozhenyuan, the clinical curative effect of hypertension and coronary heart disease. Methods Convenient collected in February 2013 to August 2015 in Changchun Medical hospital high blood fat, high blood pressure and coronary heart disease 200 case patients, divided into 100 case research group and 100 case control group. The control group took antihypertensive and lipid-lowering, reduce platelet aggregation and myocardial nutrition, study group take full treatment of Manbaozhenyuan. Comparison ①Before and after treatment, the cardiac function of the two groups;②Before and after the treatment of hypertension in the two groups;③Blood lipid levels before and after treatment in the two groups;④The recurrence rate and cure rate of the two groups were compared. Results ①The two groups before treatment, systolic blood pressure and diastolic blood pressure were(155.4±14.9)mmHg,(94.2±7.5)mmHg,(156.1±15.1)mmHg,(92.1±6.7)mmHg (P>0.05); there was no significant difference between the two groups after treatment of hypertension respectively (135.4±9.2)mmHg, (82.4±5.6)mmHg,(134.1±8.5)mmHg、 (86.7±4.2)mmHg had significant difference(P<0.05). ②Study group and control group before treatment, Ch, TG, LDL-C, BMI respectively (5.78±0.38)mmol/L, (2.54±0.36)mmol/L, (2.64±0.27)mmol/L, (25.46±1.21)kg/m2 and (5.69±0.31)mmol/L, (2.56±0.38)mmol/L, (2.65±0.31)mmol/L, (25.49±1.35)kg/m2,no difference statistical significance(P>0.05), the study group and the control group after treatment Ch, TG, LDL-C, HDL-C respectively(5.24±0.24)mmol/L, (2.37±0.28)mmol/L, (2.36±0.19)mmol/L, (24.69±1.18)kg/m2 and (5.53±0.47)mmol/L, (2.49±0.35)mmol/L, (2.51±0.22)mmol/L,(25.31±1.28)kg/m2 the difference was statistically significant (P<0.05). ③the cure rate and recurrence rate of the study group and the control group were (100%, 0%), (81%, 18%), and there were differences(P<0.05). Conclusion Manbaozhenyuan should be used as the preferred method of treatment of high blood lipids, hypertension and coronary heart disease.
[Key words] Manbaozhenyuan;High blood lipid;Hypertension;Coronary heart disease
心腦血管疾病是當(dāng)今嚴(yán)重危害人類(lèi)健康的疾病。隨著人們生活水平的改善,年齡的增加,造成心腦血管疾病的發(fā)病率日益上升。高血脂、高血壓作為心腦血管疾病發(fā)生發(fā)展的獨(dú)立危險(xiǎn)因素,會(huì)增加患者心絞痛、心肌梗死的風(fēng)險(xiǎn)。中醫(yī)將心腦血管疾病歸屬在“胸痹”“心痛”等范疇中,經(jīng)過(guò)多年的發(fā)展,各醫(yī)家總結(jié)眾多行之有效的治療方法[1]。滿(mǎn)寶珍元主要成分為樺褐孔菌、鹿心血、松茸、決明子及生曬參等。……