

[摘要] 目的 研究相同低劑量不同濃度羅哌卡因用于超聲引導(dǎo)臂叢神經(jīng)阻滯的臨床效果。方法 隨機(jī)選取2015年1月—2016年6月期間在該院進(jìn)行上肢手術(shù)的患者90例,隨機(jī)分為低濃度組(0.375%鹽酸羅哌卡因)、中濃度組(0.500%鹽酸羅哌卡因)和高濃度組(0.750%鹽酸羅哌卡因),30例/組。對(duì)比3組行上肢手術(shù)患者的麻醉效果、神經(jīng)完全阻滯率以及不同時(shí)間點(diǎn)的血藥濃度變化。結(jié)果 低濃度組的感覺(jué)阻滯起效時(shí)間(10.36±1.78)min、運(yùn)動(dòng)阻滯起效時(shí)間(12.45±2.86)min、阻滯神經(jīng)節(jié)段數(shù)(5.42±0.65)個(gè)、鎮(zhèn)痛維持時(shí)間(600.42±31.37)min、運(yùn)動(dòng)恢復(fù)時(shí)間(589.31±32.46)min方面、神經(jīng)完全阻滯率以及不同時(shí)間點(diǎn)的血藥濃度變化與中濃度組和高濃度組相比差異有統(tǒng)計(jì)學(xué)意義(P<0.05),中濃度組和高濃度之間對(duì)比,差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)。結(jié)論 在超聲引導(dǎo)臂叢神經(jīng)阻滯中使用小劑量中濃度羅哌卡因的麻醉效果顯著。
[關(guān)鍵詞] 臂叢神經(jīng)阻滯;羅哌卡因;超聲
[中圖分類號(hào)] R614 [文獻(xiàn)標(biāo)識(shí)碼] A [文章編號(hào)] 1674-0742(2016)12(c)-0110-03
[Abstract] Objective To study the clinical effect of low dose and different concentration of ropivacaine for ultrasound-guided brachial plexus block. Methods Random selection 90 patients were randomly divided into low concentration group(0.375%ropivacaine hydrochloride),medium concentration group(0.500%ropivacaine hydrochloride)and high concentration group(0.750%ropivacaine hydrochloride),30 patients/group. Comparison of the indicators. Results The onset time of sensory block(10.36±1.78)min,the onset time of motor block(12.45±2.86)min,the number of nerve block segments(5.42±0.65),the analgesic maintenance time(600.42±31.37)minand recovery time of exercise(589.31±32.46)min. There were significant differences in the total nerve block rate and the plasma concentrations at different time points compared with the medium and high concentration groups(P<0.05). There was no significant difference between concentration group and high concentration(P>0.05). Conclusion The use of low-dose midazolam in anesthesia with ultrasound-guided brachial plexus block is effective.
[Key words] Brachial plexus block;Ropivacaine; Ultrasonic
羅哌卡因由于存在起效快、藥效持久[1]等優(yōu)點(diǎn),逐漸替代布比卡因應(yīng)用在手術(shù)中。超聲引導(dǎo)臂叢神經(jīng)阻滯在臨床中廣泛應(yīng)用,但不同濃度羅哌卡因的臨床效果和安全性在臨床上的爭(zhēng)議較大。該院將2015年1月—2016年6月間行上肢手術(shù)的患者90例作為此次的研究對(duì)象,現(xiàn)報(bào)道如下。
1 資料與方法
1.1 一般資料
隨機(jī)選取該院收治的行上肢手術(shù)患者90例按計(jì)算機(jī)隨機(jī)分為3組,每組患者30例。低濃度組:男17例,女13例,年齡24~67歲,平均年齡(42.62±4.28)歲,體重51~78(61.28±4.25)kg。中濃度組:男16例,女14例,年齡25~69歲,平均年齡(44.67±4.32)歲,體重50~79kg,平均體重(61.45±4.28)kg。高濃度組:男18例,女12例,年齡25~68歲,平均年齡(43.01±4.35)歲,體重52~80kg,平均體重(61.34±4.30)kg。……