

[摘要] 目的 研究肝硬化疾病者應用生化檢驗項目診斷的價值。 方法 分析2014年10月—2016年10月該院整群選擇的肝硬化疾病102例患者資料,將其設為觀察組,另選取同期該院健康體檢者102名為對照組,對兩組生化檢驗項目進行檢驗及對比。結果 對照組總蛋白、膽堿酯酶、總膽紅素和丙氨酸氨基轉移酶等生化檢驗項目水平及纖維化指標水平均比觀察組優(P<0.05);肝硬化Child-Pugh分級A級白蛋白(40.50±3.83)g/L、膽堿酶脂(3 278.50±1 362.10)U/L和膽汁酸水平(15.98±8.05)μmol/L均比B、C級優(P<0.05)。 結論 肝功能良好者生化檢驗項目水平佳,臨床生化檢驗項目和纖維化指標均能夠為肝硬化疾病診斷提供重要參考,從而積極采取有效防治舉措,促進患者病情緩解和預后改善。
[關鍵詞] 生化項目;肝硬化疾病;纖維化指標;肝硬化分級
[中圖分類號] R5 [文獻標識碼] A [文章編號] 1674-0742(2016)12(c)-0024-03
[Abstract] Objective To study the diagnostic value of biochemical tests in patients with liver cirrhosis. Methods Group selection 102 cases of patients with liver cirrhosis selected in our hospital from October 2014 to October 2016 were enrolled in the study. 102 cases healthy subjects in the same hospital were selected as the control group. The results of the biochemical tests were compared between the two groups. Results The levels of total protein, cholinesterase, total bilirubin and alanine aminotransferase in the control group were significantly higher than those in the observation group(P<0.05). The Child-Pugh classification (40.80±3.83) g/L, cholinase (3 278.50±1 362.10) U/L and bile acid level (15.98±8.05)μmol/L of Grade A were higher than those of Grade B and C(P<0.05). Conclusion The biochemical test items with good liver function, the clinical biochemical test items and the fibrotic indexes could provide an important reference for the diagnosis of cirrhosis, and take an effective measures to promote the patients' remission and prognosis.
[Key words] Biochemical items; Cirrhosis of the liver; Fibrosis indicators; Cirrhosis grading
肝硬化屬于臨床常見肝臟疾病之一,具有較高發病率,考慮其早期臨床癥狀不顯著,易被臨床醫師和患者忽視而加重病情,對患者生命安全造成嚴重威脅,需于疾病早期尋求有效診斷指標;對于肝硬化,臨床一般采取尿常規、血常規和免疫學指標等檢驗,伴隨生化項目增多與技術成熟,其診斷準確性不斷提高[1-3]。該研究針對該院2014年10月—2016年10月已選定的肝硬化疾病102例患者和同期健康體檢者102名生化檢驗項目和纖維化指標水平及肝硬化分級生化檢驗項目水平加以對比、分析,旨在為臨床防治方案實施提供依據,改善患者預后,現報道如下。
1 資料與方法
1.1 一般資料
分析該……