止嗽散加味治療感冒后咳嗽療效觀察

摘要：目的 觀察止嗽散加味治療感冒后咳嗽的臨床療效。方法 將100感冒后咳嗽患者隨機分為兩組，治療組予止嗽散加味治療，對照組予酮替芬和復方甘草口服液治療，比較兩組的臨床療效。結果 治療組治愈33例，好轉10例，無效7例，總有效率86.00%，對照組治愈20例，好轉14例，無效16例，總有效率68.00%，兩組療效比較差異有統計學意義（P<0.05），對照組出現嗜睡、乏力、口干等不良反應。結論 止嗽散加味治療感冒后咳嗽療效優于酮替芬聯合復方甘草口服液。

關鍵詞：感冒后咳嗽；止嗽散加味；療效

Abstract：Objective To investigate the curative effect of Modified Zhisou Powder on cough post infectious. Methods 100 patients were divided into two groups according to the method of random. Treatment group was treated by Modified Zhisou Powder. Control group was treated by Ketotifen and Compound glycyrrhiza oral solution. The curative effect was compared between two groups. Results 33 cases had been cured，10 cases had been better，7 cases were invalid in treatment group. The total effective rate of treatment group was 86.00%.20 cases had been cured，14 cases had been better，16 cases were invalid in control group. The total effective rate of control group was 68.00%.The difference of curative effect between two groups was significant （P<0.05）.There was some unhealthy symptoms，such as hypersomnia， acratia and dry mouth in control group etc. Conclusion The curative effect of Modified Zhisou powder on Cough post Infectious is better than Ketotifen and Compound glycyrrhiza oral solution.

Key words：Cough post Infectious；Modified Zhisou powder；Curative Effect

感冒后咳嗽（cough post infectious，CPI）臨床常見癥狀，往往表現為陣發性刺激性嗆咳，咳嗽劇烈時可見小便自遺、嘔吐等不適，伴有咽干、咽癢等癥狀。冷、熱、油煙或刺激性氣體會誘發咳嗽不止，應用抗生素、鎮咳藥效果不好。筆者應用止嗽散加味治療此類咳嗽，療效滿意，特報道如下。

1 資料與方法

1.1一般資料 選擇符合《咳嗽的診斷與治療指南》[1]感冒后咳嗽患者，簽署知情同意書后，按就診時序隨機分為兩組。治療組50例中男24例，女26例，年齡18～50歲，平均（33.62±8.99）歲，病程15～50 d，平均（25.14±8.85）d；對照組50例中男27例，女 23例，年齡19～55歲，平均（33.76±9.04）歲，病程15～53 d，平均（25.22±9.65）d。患者在性別、年齡、病程、病情等方面的差異無統計學意義（P>0.05），具有可比性。

1.2方法

1.2.1治療組 止嗽散加味治療。藥物組成：基本方：桔梗6 g、紫苑10 g、荊芥10 g、百部10 g、陳皮6 g、白前10 g、甘草6g、蘆根15 g、白術10 g、柴胡10 g，偏肺熱加用桑白皮10 g、魚腥草20 g，偏寒者加用細辛3 g、紫蘇15 g，陰虛者加用麥門冬15 g、沙參15 g、枇杷葉10 g，水煎服，1劑/d，7 d為1療程。

1.2.2對照組 予酮替芬（上海復旦復華藥業有限公司生產）1mg口服，2次/d；……