尹燕平 劉文英



【摘要】目的:探討介入栓塞術對子宮肌瘤治療前后子宮血供變化情況的影響。 方法:選擇2014年6月至2015年6月我院婦科接診的40例子宮肌瘤患者,對所有患者進行子宮動脈介入栓塞術進行治療,觀察治療前后子宮肌瘤內部和子宮肌瘤周邊的血供參數、子宮體積、子宮肌瘤體積、平均月經量、平均月經期以及卵巢中相關激素的變化情況。結果:患者治療后子宮肌瘤內部血供中的收縮期峰值流速(4.15±0.64)cm/s、平均流速(1.95±0.41)cm/s、最粗供血動脈管徑(8.22±1.10)mm均低于治療前[(21.38±4.39)cm/s、(12.58±2.14)cm/s、(31.14±3.42)mm],阻力指數(0.98±0.10)得到上升(0.51±0.05),子宮肌瘤周邊血供中的收縮期峰值流速、平均流速、最粗供血動脈管徑也低于治療前,阻力指數高于治療前,差異具有統計學意義(P<0.05);治療后子宮體積和子宮肌瘤體積(154.32±25.28,17.84±5.95)cm3明顯小于治療前(326.87±43.64,57.59±15.48)cm3,平均月經量(47.23±9.51)mL和平均月經期(4.76±1.09)d低于治療前[(86.84±17.48)mL、(7.83±1.52)d],治療前后相比,差異具有統計學意義(P<0.05)。結論:介入栓塞術可以有效的降低子宮肌瘤患者的血供情況,不僅保留了子宮,還能良好的保護患者的卵巢功能,值得在臨床上應用推廣。
【關鍵詞】子宮動脈介入栓塞術;子宮肌瘤;血供變化
Effect of interventional embolization on the uterine blood supplyand ovarian function of patients with uterine fibroidsYIN Yanping1, LIU Wenying2. 1.Department of Obstetrics and Gynecology, Zigong Third Peoples Hospital, Zigong 643020, Sichuan, China;2.Department of Obstetrics and Gynecology, Zigong fourth Peoples Hospital, Zigong 643000, Sichuan, China
【Abstract】Objectives: To investigate the effect of interventional embolization on the changes of uterine blood supply before and after the treatment of uterine fibroids. Methods: 40 patients with uterine fibroids in our hospital from June 2014 to June 2015 were selected and treated with interventional embolization. The blood supply parameters, uterine volume, the volume of uterine fibroids, the average menstrual volume, the average menstrual period, and the changes in related hormones were observed. Results: The peak flow velocity (4.15±0.64)cm/s, average flow velocity (1.95±0.41)cm/s and the diameter of the most crude blood supply artery (8.22±1.10)mm were lower than those before treatment [(21.38±4.39)cm/s, (12.58±2.14)cm/s, (31.14±3.42)mm]; the resistance index (0.98±0.10) was increased (0.51±0.05); the peak flow velocity, average flow velocity and the diameter of the blood supply in the peripheral blood supply of uterine fibroids were lower than those before treatment, and the resistance index was higher than before treatment, all with statistically significant difference (P<0.05). After treatment, uterine volume and uterine myoma volume (154.32±25.28, 17.84±5.95) cm3 were significantly smaller than before treatment (326.87±43.64, 57.59±15.48)cm3 ); the average menstrual volume (47.23±9.51) ml and the average period (4.76±1.09) d were lower than before treatment, [(86.84±17.48)ml, (7.83±1.52)d], both with statistically significant difference (P<0.05). Conclusions: Interventional embolization can effectively reduce the uterine blood supply of patients with uterine fibroids, which not only retains the uterus, but also protects ovarian function, thusly worthy of promotion in clinical application.
【Key words】Uterine artery embolization; Uterine fibroid; Changes in blood supply
【中圖分類號】R737.33【文獻標志碼】A
子宮肌瘤在女性的生殖系統中是一種較為常見的良性腫瘤,在婦科中也是一種多發的病癥[1,2]。有文獻報道,子宮肌瘤患者對雌激素有一定的依賴性,臨床上常表現為月經量增多、月經周期長,還伴隨著痛經、貧血等癥狀,子宮肌瘤還容易使患者鄰近器官受到壓迫,引起尿頻、尿急及便秘等情況的發生,影響了患者日常的生活質量,嚴重的還會對其生育功能造成影響[2,3]。有研究顯示,對子宮肌瘤患者肌瘤血供的情況進行控制是一種有效的治療方法,傳統的臨床治療方式是對患者通過藥物以及手術治療,但結果并不令人滿意[4,5]。隨著目前動脈介入栓塞術對子宮肌瘤患者的普遍應用,有報道顯示該術在子宮肌瘤患者中有著良好的療效[6]。……