金銀花湯聯(lián)合青霉素治療梅毒效果觀察

陳海挺 胡江飚 盧敏攀 寧維翾

【摘要】目的：探討金銀花湯聯(lián)合青霉素治療梅毒效果。方法：選取2013年1月至2015年1月于我院與杭州市中醫(yī)院接受治療的120患者為研究對(duì)象，按照自愿原則，將其均分為觀察組和對(duì)照組。對(duì)照組單純采用青霉素進(jìn)行治療；觀察組采用金銀花湯聯(lián)合青霉素進(jìn)行治療。比較兩組隨訪結(jié)果及治療有效率。結(jié)果：觀察組平均有效時(shí)間為（0.79±0.23）d，平均治愈時(shí)間為（2.47±0.29）d，PRP轉(zhuǎn)陰率為91.67%；對(duì)照組分別為（1.61±0.27）d、（3.52±0.44）d、70.00%，觀察組隨訪結(jié)果明顯優(yōu)于對(duì)照組（P<0.05）。兩組患者病情均有一定程度的改善，其中觀察組中顯效的有52例，有效的有3例，無(wú)效的僅有5例，而對(duì)照組相應(yīng)為25例、17例、18例，對(duì)照組治療有效率明顯低于觀察組（P<0.05）。結(jié)論：金銀花湯聯(lián)合青霉素能有效縮短痊愈時(shí)間、提高PRP轉(zhuǎn)陰率、提升治療有效率，臨床效果顯著。

【關(guān)鍵詞】金銀花湯；青霉素；梅毒；效果觀察

Effect of honeysuckle soup with penicillin in the treatment of syphilisCHEN Haiting1， HU Jiangbiao1， LU Minpan1， NING Weixuan2. 1. Department of Rehabilitation Medicine of Chinese Medicine，Yongkang First Peoples Hospital， Jinhua 321300， Zhejiang， China； 2. Dermatology Department，Hangzhou Traditional Chinese Medical Hospital， Hangzhou 310000， Zhejiang， China

【Abstract】Objectives： To explore the effect of honeysuckle soup combined penicillin in the treatment of syphilis. Methods： 120 patients in Yongkang First Peoples Hospital and Hangzhou Traditional Chinese Medical Hospital from January 2013 to January 2015 were selected as research objects， and in accordance with the principle of voluntary， were divided into observation group and control group. Control group simply received penicillin treatment； while the observation group received honeysuckle soup combined penicillin treatment. The treatment effectiveness and follow-up results were compared between the two groups. Results： The average effective time， average healing time and PRP negative conversion ratio in observation group were （0.79±0.23） d， （2.47±0.29） d and 91.67% respectively， while those in the control group were （1.61±0.27）d， （3.52±0.44） d and 70.00% accordingly. The follow-up results of observation group were obviously better than that of control group （P<0.05）. The condition of patients in both groups was improved to a certain extent， where 52 cases took effect， 3 cases proved effective and 5 cases ineffective in the observation group， and those in the control group were 25 cases， 17 cases and 18 cases respectively， with significant difference between the two groups （P<0.05）. Conclusion： Honeysuckle soup combined penicillin can effectively shorten the healing time， increase the PRP negative conversion ratio and promote efficient treatment， with remarkable treatment effect.

【Key words】Honeysuckle soup； Penicillin； Syphilis； Results observation

【中圖分類(lèi)號(hào)】R759.1【文獻(xiàn)標(biāo)志碼】A

梅毒是一種慢性傳染性疾病，屬于多器官疾病，其傳播媒介是蒼白螺旋體，傳播途徑主要是直接或間接的性接觸、母嬰傳播、輸血等[1]。研究表明，目前我國(guó)梅毒的發(fā)病情況呈現(xiàn)上升趨勢(shì)，梅毒由于其傳染性給患者的生活帶來(lái)了極大的不便，也給患者帶來(lái)了極大的精神壓力，嚴(yán)重影響患者的生活質(zhì)量和健康狀況[2]。目前治療梅毒的常用藥物主要是芐星青霉素、頭孢三嗪等，為了探討金銀花湯聯(lián)合青霉素治療梅毒效果，我院嘗試開(kāi)展本研究?，F(xiàn)報(bào)道如下。

1資料與方法

1.1一般性資料

選取2013年1月至2015年1月于我院與杭州市中醫(yī)院皮膚科接受治療的患者為研究對(duì)象，按照自愿原則，將其均分為觀察組和對(duì)照組，每組患者60例。納入標(biāo)準(zhǔn)：（1）所有患者均符合衛(wèi)生部防疫司《性病防治手冊(cè)》中梅毒的臨床診斷標(biāo)準(zhǔn)；（2）經(jīng)過(guò)實(shí)驗(yàn)室根據(jù)患者體征及實(shí)驗(yàn)室檢測(cè)RPR、梅毒螺旋體抗體明膠顆粒試驗(yàn)（TPPA）均為陽(yáng)性；……