鄧輝+馬春清+祝存海



【摘要】目的:探討經尿道等離子雙極電切除術治療良性前列腺增生對患者尿道功能和性功能的影響。方法:選擇122例良性前列腺增生患者為研究對象,隨機分為觀察組和對照組各61例,觀察組采用經尿道雙極等離子電切術(PKRP),對照組采用經尿道前列腺電切術(TURP),比較兩組手術指標、尿道功能、血紅蛋白與紅細胞壓積、性功能等指標。結果:兩組患者在年齡、病史、前列腺體積、IPSS評分、QOL評分、術前血紅蛋白水平等一般資料方面無明顯統計學差異,具有可比性。(1)手術指標:觀察組術中出血量、置管時間、術后住院時間均明顯低于對照組[(63.12±7.45 vs. 118.75±13.24)mL、 (3.98±1.12 vs. 5.76±1.65)d、 (5.65±1.22 vs. 7.16±1.68)d](P<0.05、0.01);(2)尿道功能:觀察組Qmax明顯高于對照組(14.68±2.14 vs. 13.42±2.06)mL/s,RU、IPSS、QOL均明顯低于對照組[(18.35±3.24 vs. 24.32±3.54)mL、 (7.68±1.25 vs. 10.12±1.32)分、 (1.82±0.54 vs. 2.12±0.62)分](P<0.05);(3)血紅蛋白與紅細胞壓積:觀察組血紅蛋白、紅細胞壓積下降值均明顯低于對照組[(11.12±2.18 vs. 16.56±2.34)g/L、 (3.08±0.58 vs. 4.95±1.02)%](P<0.01);(4)性功能:觀察組IIEF-5評分明顯高于對照組[(23.45±3.24 vs. 21.32±3.12)]分(P<0.05),陰莖勃起障礙、逆行射精發生率均明顯低于對照組[(1.64% vs. 9.84%、 32.79% vs. 47.54%)](P<0.05)。結論:經尿道等離子雙極電切術具有手術創傷小、恢復快的優點,有利于改善患者尿道功能,對機體功能影響較小。
【關鍵詞】良性前列腺增生;等離子雙極電切除術;尿道功能;性功能
Impact of transurethral plasmakinetic resection of prostate on urethral function and sexual function in patients with benign prostatic hyperplasiaDENG Hui, MA Chunqing△, ZHU Cunhai. Department of Urology, Xiaogan Central Hospital, Xiaogan 432000, Hubei, China
【Abstract】Objectives: To study the effect of transurethral plasmakinetic resection of prostate (TPRP) on urethral function and sexual function in patients with benign prostatic hyperplasia. Methods: 122 patients with benign prostatic hyperplasia were divided into observation group and control group. The observation group was given TPRP, while the control group was given transurethral resection of prostate (TURP).The operation index, urethra function, hemoglobin, red blood cells deposited and sexual function of the two groups were compared. Results: There was no statistically significant differences in the postoperative decline of hemoglobin levels, postoperative hospital stay, and quality of life score (QOL), operation time, International Prostate Symptom Score (IPSS) and other aspects between the two groups. (1) Operation: intraoperative blood loss, catheter time, postoperative hospital stay of observation group were significantly lower than these in control group [(63.12±7.45 vs 118.75±13.24)ml, (3.98±1.12 vs 5.76±1.65, 5.65±1.22 vs 7.16±1.68)d (P<0.05, 0.01); (2)Urethra function: Qmax of observation group was significantly higher than that of control group (14.68±2.14 vs 13.42±2.06)ml/s, and RU, IPSS, QOL were significantly lower than these in control group [(18.35±3.24 vs 24.32±3.54)ml, (7.68±1.25 vs 10.12±1.32, 1.82±0.54 vs 2.12±0.62)] (P<0.05). (3) Hemoglobin and red blood cells deposited: hemoglobin, red blood cells decline value of observation group were significantly lower than these in control group [(11.12±2.18 vs 16.56±2.34)g/L, (3.08±0.58 vs 4.95±1.02)%] (P<0.01); (4)Sexual function: IIEF - 5 score of observation group was significantly higher than that of control group (23.45±3.24 vs 21.32±3.12) (P<0.05), penile erectile dysfunction, retrograde ejaculation were significantly lower than these in control group (1.64% vs 9.84%, 32.79% vs 47.54%) (P<0.05). Conclusion: Transurethral plasmakinetic resection of prostate has the advantages of small surgical trauma, rapid recovery and it can improve the function of urinary tract, with less effect on the body function.endprint
【Key words】Benign prostatic hyperplasia; Transurethral plasmakinetic resection of prostate; Urethral function; Sexual function
【中圖分類號】R697+.3【文獻標志碼】A
前列腺增生(benign prostate hyperplasia,BPH)是老年男性中常見泌尿系統疾病,及時解除膀胱流出道梗阻是治療良性前列腺增生的關鍵。經尿道前列腺切除術(Transurethral Resection of Prostate, TURP)一直被視為治療前列腺良性增生的“金標準”,但術中易引發出血、包膜穿孔、術中電切癥(TURS)、性功能障礙以及二次手術[1]。經尿道雙極等離子電切術(Transurethral plasma kinetic resection of prostate, PKRP)通過高頻電流激發生理鹽水介質形成動態等離子,作用于靶組織產生電化切割與電凝效果,可有效減少TURP手術并發癥[2]的發生。本文采取隨機對照研究的方法,探討TPRP術對良性前列腺增生患者尿道功能與性功能的影響。
1資料與方法
1.1一般資料
選擇我院泌尿外科2012年12月至2014年1月收治的122例良性前列腺增生患者為研究對象,年齡61~85歲,平均年齡(57.30±5.65)歲;根據Rous標準判定:前列腺腫大Ⅰ度43例,Ⅱ度45例,Ⅲ度34例;……