彭克學+諶珩+李娓+韓愈


【摘要】目的:觀察經尿道選擇性綠激光前列腺汽化術(greenlight photoselective vaporization of prostate,PVP)與經尿道前列腺電切術(TURP)治療高齡高危良性前列腺增生(benign prostatic hyperplasia,BPH)的臨床療效及安全性分析。方法:臨床納入高齡高危BPH患者90例,根據手術方案的不同分為研究組與對照組,研究組進行PVP,對照組進行TURP。觀察兩組患者術前、術后1個月、術后12個月最大尿流率(Qmax)、殘余尿量(PVR)以及國際前列腺癥狀評分(IPSS)等,對比兩組患者術后并發癥的發生率。結果:術前及術后1個月,兩組患者Qmax、PVR、IPSS差異均無顯著性(P>0.05);術后12個月,研究組Qmax、PVR、IPSS分別為(19.79±5.07)mL/s、(12.69±15.58)mL、(4.92±2.17)分,對照組Qmax、PVR、IPSS分別為(17.98±4.52)mL/s、(23.54±26.66)mL、(7.47±2.02)分,差異均有顯著性(P<0.05);研究組術后低鈉血癥發生率與輸血發生率分別為6.67%、2.22%,對照組術后低鈉血癥發生率與輸血發生率分別為22.22%、13.33%,差異均有顯著性(P<0.05)。結論:PVP治療高齡高危BPH的中期療效優于TURP,能夠有效改善患者的排尿,且術后并發癥發生率較低,值得推廣。
【關鍵詞】經尿道選擇性綠激光前列腺汽化術;經尿道前列腺電切術;良性前列腺增生
Clinical research of pvp on the treatment of elderly high-risk benign prostatic hyperplasiaPENG Kexue, CHEN Heng, LI Wei, HAN Yu. Urology Department, Hubei Province Rongjun Hospital, Wuhan 430079, Hubei, China
【Abstract】Objectives: To observe and analyze the clinical effects of greenlight photoselective vaporization of the prostate (PVP) and transurethral resection of the prostate (TURP) on the treatment of elderly high-risk benign prostatic hyperplasia (BPH). Methods: 90 patients with elderly high-risk BPH were selected and divided into research group and control group based on different operation methods. The research group was given PVP, while the control group was given TURP. The Qmax, PVR, and IPSS of patients in both groups before operation, and 1 month, and 12 months after operation were observed. In addition, postoperative complication rates of both groups were observed. Results: Before operation and 1 month after operation, the Qmax, PVR, and IPSS of patients in both groups showed no significant difference (P> 0.05);12 months after operation, the Qmax, PVR, and IPSS of the research group were respectively (19.79±5.07 ml/s, (12.69±15.58) ml, and (4.92±2.17) points, while for the control group respectively (17.98±4.52 ml/s, (23.54±26.66) ml, and (7.47±2.02) points. The differences were significant (P< 0.05); The postoperative hyponatremia and blood transfusion rate of the research group were 6.67% and 2.22%, while 22.22% and 13.33% for the control group. The differences were significant (P< 0.05). Conclusion: The mid-term effect of PVP is better than TURP on the treatment of elderly high-risk BPH. It can effectively improve patients urine with lower postoperative complication rate, which is worth promotion.
【Key words】Greenlight photoselective vaporization of prostate (PVP); Transurethral resection of the prostate (TURP); Benign prostatic hyperplasiaendprint
【中圖分類號】R697+.3【文獻標志碼】A
良性前列腺增生(benign prostatic hyperplasia,BPH)屬于臨床常見的一種以膀胱出口梗阻為主要表現的疾病[1]。研究表明,BPH的發病率隨著年齡的增加出現顯著升高的趨勢。在70歲以上的老年患者中,尤其是合并重要器官疾病時,被臨床稱為高齡高危BPH[2,3]。手術是目前臨床上治療BPH較為有效的一種方式,并得到了廣泛的開展[4]。目前,臨床上用于治療BPH的手術方案較多,常見的有經尿道鈥激光前列腺剜除術(HoLEP)、經尿道前列腺電切術(TURP)[5],近年來,PVP在臨床上逐漸開展應用。筆者采用PVP治療高齡高危BPH,取得了較好的臨床療效,現報告如下。
1資料和方法
1.1一般資料
本文納入90例我院2010年1月至2014年1月期間收治的高齡高危BPH手術患者作為研究對象,所有患者均同意手術治療。根據手術方式將患者分為兩組各45例。研究……