沈陽市1010例不孕不育癥患者病因分析

肖育紅 周敏 齊倩 白璐 張麗麗

【摘要】目的：研究分析沈陽市1010例不孕不育癥患者病因。方法：選擇2012年6月至2014年12月在我院接受診斷及治療的1010例不孕不育患者進(jìn)行研究，為所有患者進(jìn)行檢查，記錄導(dǎo)致患者不孕不育的病因，使用Logistic回歸分析法評(píng)價(jià)影響男女患者不孕不育的危險(xiǎn)因素。結(jié)果：女性不孕的病因在原發(fā)不孕及繼發(fā)不孕的患者中均以排卵障礙為主，其次為輸卵管病變。原發(fā)不孕與繼發(fā)不孕患者在病因上對比，差異無統(tǒng)計(jì)學(xué)意義（P>0.05）。 原發(fā)不育的病因主要為弱精子癥和精液不液化，以及畸精子癥，而繼發(fā)不育的主要病因是弱精子癥和畸精子癥，以及少精子癥。原發(fā)不育與繼發(fā)不育患者在病因上對比，差異無統(tǒng)計(jì)學(xué)意義（P>0.05）。通過Logistic回歸分析法評(píng)價(jià)可知，影響女性不孕的危險(xiǎn)因素為排卵障礙及輸卵管病變，影響男性不育的危險(xiǎn)因素為弱精子癥及畸精子癥。結(jié)論：沈陽市不孕不育患者的病因較多，臨床上應(yīng)給予積極的健康宣教以及合理的預(yù)防措施，從而盡可能地降低不孕不育患者的發(fā)病比例，值得重視。

【關(guān)鍵詞】沈陽市；不孕不育癥；病因分析

Etiology analysis of 1010 cases of infertility in Shenyang cityXIAO Yuhong1， ZHOU Min1， QI Qian1， BAI Lu1， ZHANG Lili2. 1. Eugenics Center， The 202 Hospital of PLA， Shenyang 110003， Liaoning， China； 2. Department of Obstetrics and Gynaecology， Shulan Peoples Hospital， Jilin 132600， Liaoning， China

【Abstract】Objectives： To study etiology of 1010 infertility patients in Shenyang city. Methods： 1010 cases of infertility in our hospital from June 2012 to December 2014 were selected and examined. The causes of infertility were recorded. Regression analysis of risk factors for male and female patients with infertility was evaluated using logistic method. Results： The etiology of female infertility in primary infertility and secondary infertility in patients was mainly ovulation disorder， followed by tubal disease. The difference of causes in primary infertility and secondary infertility had no statistical significance （P>0.05）. The main causes of primary infertility were asthenospermia， semen liquefaction and teratozoospermia. The main causes of secondary infertility were asthenospermia， teratozoospermia and oligospermia. For primary infertility and secondary infertility， there was no significant difference in etiology （P>0.05）. By logistic regression analysis， the risk factors of female infertility were ovulation and tubal disease. Risk factors for male sterility were asthenospermia and teratozoospermia. Conclusion： The etiology of Shenyang infertility patients is complicated. Clinical doctors should give positive health education and reasonable preventive measures， so as to reduce the incidence of infertility patients.

【Key words】Shenyang； Infertility； Etiological analysis

【中圖分類號(hào)】R711.6；R698+.2【文獻(xiàn)標(biāo)志碼】A

伴隨我國人民生活環(huán)境的不斷改變，不孕不育患者的比例逐年上升。在臨床上，不孕不育主要是夫妻雙方均在規(guī)律性生活1年后仍無法發(fā)生受孕生育的一種疾病，分原發(fā)性及繼發(fā)性兩類，均為生殖健康缺陷[1]。國外Noveski P等人[2]報(bào)道指出，導(dǎo)致不孕不育的原因較多，進(jìn)行有效治療的重要前提是找出具體病因。因此，為……