非ST抬高型ACS患者竇性心律震蕩與ST—T及超敏肌鈣蛋白關系分析

王海林+王培寧+黃慶彬

[摘要] 目的 探討非ST抬高型急性冠狀動脈綜合征（acute coronary syndrome，ACS）患者竇性心律震蕩與ST-T及超敏肌鈣蛋白關系分析。 方法 回顧性分析2014年9月～2016年5月期間我院及廣東省人民醫院確診治療的非ST抬高型ACS患者62例，依據是否伴有竇性心律震蕩異常分為異常組（n=28例）和正常組（n=34例），所有患者均給予經心臟彩超、動態心電圖等檢查，采用酶聯免疫吸附法檢測血清超敏肌鈣蛋白T（hypersensitive troponin T，hs-TnT）水平，采用Pearson相關性分析法分析震蕩初始值（turbulence onset，TO）、震蕩斜率（turbulence slope，TS）水平與ST-T壓低、血清hs-TnT水平的關系。 結果 異常組患者TO、ST-T壓低、血清hs-TnT水平明顯高于正常組，前者TS水平明顯低于后者，差異有統計學意義（P<0.05）；Pearson相關性分析法結果顯示，TO水平與ST-T壓低、血清hs-TnT水平呈正相關（r1=0.731，P<0.05；r2=0.702，P<0.05），TS水平與ST-T壓低、血清hs-TnT水平呈負相關（r3=-0.714，P<0.05；r4=-0.685，P<0.05）。 結論 非ST抬高型ACS患者竇性心律震蕩中的TO、TS水平與ST-T壓低及血清hs-TnT水平有關，提示其也具有有效反映患者病情的作用，可作為患者病情新的心電評估指標之一，值得臨床作進一步推廣。

[關鍵詞] 非ST抬高型急性冠狀動脈綜合征；竇性心律震蕩；ST-T；超敏肌鈣蛋白

[中圖分類號] R542.22 [文獻標識碼] A [文章編號] 2095-0616（2017）13-254-04

[Abstract] Objective To explore relationship analysis of sinus rhythm turbulence and ST-t and high-sensitivity troponin of patients with non-ST elevation acute coronary syndrome（ACS）. Methods 62 patients with Non-ST Elevation ACS who were diagnosed and treated in our hospital and Guangdong General Hospital from September 2014 to May 2016 were retrospectively analyzed.According to sinus rhythm turbulence abnormality，all patients were divided into the abnormal group（n=28） and the normal group（n=34）.All patients were given heart color ultrasound，dynamic electrocardiogram and other examinations.Hypersensitive troponin T（hs-TnT） level was detected by enzyme-linked immunosorbent assay.Relationship between turbulence onset （TO） and turbulence slope（TS） and ST–T lowering and serum hs-TnT level was analyzed by Pearson correlation analysis. Results TO，ST-t lowering and serum hs-TnT levels of patients in the abnormal group were significantly higher than those of the normal group while TS was significantly lower than that of the normal group.There were statistical differences（P<0.05）.Results of Pearson correlation analysis showed TO level，ST–T lowering and serum hs-TnT level were positively correlated（r1=0.731，P<0.05；r2=0.702，P<0.05）.TS level，ST–T lowering and serum hs-TnT level werenegatively correlated （r3=0.714，P<0.05；r4=0.685，P<0.05）. Conclusion For patients with non-ST elevation acute coronary syndrome，TO level and TS level are correlated to ST–T lowering and serum hs-TnT level.It indicates its effect of effectively reflecting diseases of patients and it can be regarded as the new ECG evaluation index，which is worthy of further clinical promotion.

[Key words] Non-ST elevation acute coronary syndrome；Sinus rhythm turbulence；ST-T；High-sensitivity troponin

[摘要] 目的 探討非ST抬高型急性冠狀動脈綜合征（acute coronary syndrome，ACS）患者竇性心律震蕩與ST-T及超敏肌鈣蛋白關系分析。 方法 回顧性分析2014年9月～2016年5月期間我院及廣東省人民醫院確診治療的非ST抬高型ACS患者62例，依據是否伴有竇性心律震蕩異常分為異常組（n=28例）和正常組（n=34例），所有患者均給予經心臟彩超、動態心電圖等檢查，采用酶聯免疫吸附法檢測血清超敏肌鈣蛋白T（hypersensitive troponin T，hs-TnT）水平，采用Pearson相關性分析法分析震蕩初始值（turbulence onset，TO）、震蕩斜率（turbulence slope，TS）水平與ST-T壓低、血清hs-TnT水平的關系。 結果 異常組患者TO、ST-T壓低、血清hs-TnT水平明顯高于正常組，前者TS水平明顯低于后者，差異有統計學意義（P<0.05）；Pearson相關性分析法結果顯示，TO水平與ST-T壓低、血清hs-TnT水平呈正相關（r1=0.731，P<0.05；r2=0.702，P<0.05），TS水平與ST-T壓低、血清hs-TnT水平呈負相關（r3=-0.714，P<0.05；r4=-0.685，P<0.05）。 結論 非ST抬高型ACS患者竇性心律震蕩中的TO、TS水平與ST-T壓低及血清hs-TnT水平有關，提示其也具有有效反映患者病情的作用，可作為患者病情新的心電評估指標之一，值得臨床作進一步推廣。

[關鍵詞] 非ST抬高型急性冠狀動脈綜合征；竇性心律震蕩；ST-T；超敏肌鈣蛋白

[中圖分類號] R542.22 [文獻標識碼] A [文章編號] 2095-0616（2017）13-254-04

[Abstract] Objective To explore relationship analysis of sinus rhythm turbulence and ST-t and high-sensitivity troponin of patients with non-ST elevation acute coronary syndrome（ACS）. Methods 62 patients with Non-ST Elevation ACS who were diagnosed and treated in our hospital and Guangdong General Hospital from September 2014 to May 2016 were retrospectively analyzed.According to sinus rhythm turbulence abnormality，all patients were divided into the abnormal group（n=28） and the normal group（n=34）.All patients were given heart color ultrasound，dynamic electrocardiogram and other examinations.Hypersensitive troponin T（hs-TnT） level was detected by enzyme-linked immunosorbent assay.Relationship between turbulence onset （TO） and turbulence slope（TS） and ST–T lowering and serum hs-TnT level was analyzed by Pearson correlation analysis. Results TO，ST-t lowering and serum hs-TnT levels of patients in the abnormal group were significantly higher than those of the normal group while TS was significantly lower than that of the normal group.There were statistical differences（P<0.05）.Results of Pearson correlation analysis showed TO level，ST–T lowering and serum hs-TnT level were positively correlated（r1=0.731，P<0.05；r2=0.702，P<0.05）.TS level，ST–T lowering and serum hs-TnT level werenegatively correlated （r3=0.714，P<0.05；r4=0.685，P<0.05）. Conclusion For patients with non-ST elevation acute coronary syndrome，TO level and TS level are correlated to ST–T lowering and serum hs-TnT level.It indicates its effect of effectively reflecting diseases of patients and it can be regarded as the new ECG evaluation index，which is worthy of further clinical promotion.

[Key words] Non-ST elevation acute coronary syndrome；Sinus rhythm turbulence；ST-T；High-sensitivity troponin

[摘要] 目的 探討非ST抬高型急性冠狀動脈綜合征（acute coronary syndrome，ACS）患者竇性心律震蕩與ST-T及超敏肌鈣蛋白關系分析。 方法 回顧性分析2014年9月～2016年5月期間我院及廣東省人民醫院確診治療的非ST抬高型ACS患者62例，依據是否伴有竇性心律震蕩異常分為異常組（n=28例）和正常組（n=34例），所有患者均給予經心臟彩超、動態心電圖等檢查，采用酶聯免疫吸附法檢測血清超敏肌鈣蛋白T（hypersensitive troponin T，hs-TnT）水平，采用Pearson相關性分析法分析震蕩初始值（turbulence onset，TO）、震蕩斜率（turbulence slope，TS）水平與ST-T壓低、血清hs-TnT水平的關系。 結果 異常組患者TO、ST-T壓低、血清hs-TnT水平明顯高于正常組，前者TS水平明顯低于后者，差異有統計學意義（P<0.05）；Pearson相關性分析法結果顯示，TO水平與ST-T壓低、血清hs-TnT水平呈正相關（r1=0.731，P<0.05；r2=0.702，P<0.05），TS水平與ST-T壓低、血清hs-TnT水平呈負相關（r3=-0.714，P<0.05；r4=-0.685，P<0.05）。 結論 非ST抬高型ACS患者竇性心律震蕩中的TO、TS水平與ST-T壓低及血清hs-TnT水平有關，提示其也具有有效反映患者病情的作用，可作為患者病情新的心電評估指標之一，值得臨床作進一步推廣。

[關鍵詞] 非ST抬高型急性冠狀動脈綜合征；竇性心律震蕩；ST-T；超敏肌鈣蛋白

[中圖分類號] R542.22 [文獻標識碼] A [文章編號] 2095-0616（2017）13-254-04

[Abstract] Objective To explore relationship analysis of sinus rhythm turbulence and ST-t and high-sensitivity troponin of patients with non-ST elevation acute coronary syndrome（ACS）. Methods 62 patients with Non-ST Elevation ACS who were diagnosed and treated in our hospital and Guangdong General Hospital from September 2014 to May 2016 were retrospectively analyzed.According to sinus rhythm turbulence abnormality，all patients were divided into the abnormal group（n=28） and the normal group（n=34）.All patients were given heart color ultrasound，dynamic electrocardiogram and other examinations.Hypersensitive troponin T（hs-TnT） level was detected by enzyme-linked immunosorbent assay.Relationship between turbulence onset （TO） and turbulence slope（TS） and ST–T lowering and serum hs-TnT level was analyzed by Pearson correlation analysis. Results TO，ST-t lowering and serum hs-TnT levels of patients in the abnormal group were significantly higher than those of the normal group while TS was significantly lower than that of the normal group.There were statistical differences（P<0.05）.Results of Pearson correlation analysis showed TO level，ST–T lowering and serum hs-TnT level were positively correlated（r1=0.731，P<0.05；r2=0.702，P<0.05）.TS level，ST–T lowering and serum hs-TnT level werenegatively correlated （r3=0.714，P<0.05；r4=0.685，P<0.05）. Conclusion For patients with non-ST elevation acute coronary syndrome，TO level and TS level are correlated to ST–T lowering and serum hs-TnT level.It indicates its effect of effectively reflecting diseases of patients and it can be regarded as the new ECG evaluation index，which is worthy of further clinical promotion.

[Key words] Non-ST elevation acute coronary syndrome；Sinus rhythm turbulence；ST-T；High-sensitivity troponin