黎勇強

【摘要】 目的 探究老年重癥心力衰竭急診內科治療的方法及臨床療效。方法 60例重癥心力衰竭患者, 隨機分為實驗組和對照組, 各30例。對照組采用常規方法進行治療, 實驗組在常規治療基礎上應用美托洛爾聯合厄貝沙坦氫氯噻嗪治療, 觀察兩組的臨床療效與治療前后的左心射血分數(LVEF)、B型尿鈉肽(BNP)、美國紐約心臟病協會(NYHA)變化。結果 實驗組患者治療總有效率為93.3%, 對照組治療總有效率為73.3%;實驗組治療總有效率高于對照組, 差異有統計學意義(P<0.05)。治療前, 兩組LVEF及BNP、NYHA比較差異無統計學意義(P>0.05);治療后, 兩組LVEF及BNP、NYHA均優于治療前, 且實驗組優于對照組, 差異有統計學意義(P<0.05)。結論 老年重癥心力衰竭患者急診內科進行常規治療, 并采用美托洛爾聯合厄貝沙坦氫氯噻嗪的治療方法, 效果顯著, 值得采用。
【關鍵詞】 重癥心力衰竭;急診內科;療效觀察
DOI:10.14163/j.cnki.11-5547/r.2018.03.044
【Abstract】 Objective To investigate the treatment method and clinical efficacy of emergency internal medicine for elderly severe heart failure. Methods A total of 60 severe heart failure patients were randomly divided into experimental group and control group, with 30 cases in each group. The control group received conventional method for treatment, and the experimental group received metoprolol combined with irbesartan and hydrochlorothiazide on the basis of conventional therapy. Observation were made on clinical efficacy, changes in left ventricular ejection fraction (LVEF), B-type natriuretic peptide (BNP) and New York Heart Association (NYHA) classification before and after treatment between two groups. Results The experimental group had total treatment effective rate as 93.3%, while the control group had total treatment effective rate as 73.3%. The experimental group had higher total treatment effective rate than the control group, and the difference was statistically significant (P<0.05). Before treatment, both groups had no statistically significant difference in LVEF, BNP and NYHA (P>0.05). After treatment, both groups had better LVEF, BNP and NYHA than before treatment, and the experimental group was better than the control group. Their difference was statistically significant (P<0.05). Conclusion For elderly patients with severe heart failure, emergency internal medicine treatment of conventional medicine, along with metoprolol and irbesartan hydrochlorothiazide treatment shows remarkable effect, and it is worthy of application.
【Key words】 Severe heart failure; Emergency internal medicine; Efficacy observation
心力衰竭是因心臟結構、功能不全導致心臟收縮功能不全出現心排血量不足、各臟器供血不足的一類綜合征[1]。患者心力衰竭進行性惡化, 同時伴有心源性水腫及低鈉血癥, 是該病重要特征, 且重癥心力衰竭好發于老年人, 治療難度大, 病死率高[2]。本研究選取本院2016年7月~2017年7月收治的60例重癥心力衰竭患者, 對其中30例采取有效的急診內科治療措施, 取得了顯著效果, 現報告如下。
1 資料與方法
1. 1 一般資料 選取本院2016年7月~2017年7月收治的60例重癥心力衰竭患者作為研究對象, 所有患者不能從事體力活動, 安靜狀態下亦發病, 心功能Ⅳ級。將患者隨機分為實驗組和對照組, 各30例。實驗組中男17例, 女13例, 年齡56~73歲, 平均年齡(64.5±3.5)歲;高血壓15例, 冠心病9例, 擴張型心肌病6例。對照組中男16例, 女14例, 年齡58~77歲, 平均年齡(67.5±3.8)歲;高血壓17例, 冠心病10例, 擴張型心肌病3例。……