0.05);研究組LDL-C術后2 d(1.46±0.12)mmol/L、5 d(1.31±0.12)mmol/L、10 d(2."/>
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[摘要] 目的 分析研討腹腔鏡結直腸癌根治術對患者圍術期機體代謝及胃腸功能的影響。方法 從該院2018年1月—2019年1月期間收治的結直腸癌患者中隨機抽取92例進行討論,按治療方式分組研究組(46例腹腔鏡結直腸癌根治術治療)和對照組(46例開腹手術治療),觀察比較治療狀況,如圍術期胃腸功能、脂代謝、蛋白代謝等。結果 術前脂代謝、蛋白代謝指標差異無統計學意義(P>0.05);研究組LDL-C術后2 d(1.46±0.12)mmol/L、5 d(1.31±0.12)mmol/L、10 d(2.31±0.22)mmol/L時優于對照組(1.71±0.15)mmol/L、(1.64±0.14)mmol/L、(1.88±0.16)mmol/L,術后2 d TC(2.98±0.21)mmol/L、TG(0.94±0.08)mmol/L、術后5 d TC(2.62±0.18)mmol/L、TG(0.88±0.07)mmol/L高于對照組2 d TC(2.42±0.17)mmol/L、TG(0.82±0.06)mmol/L、5 d TC(2.15±0.14)mmol/L、TG(0.71±0.04)mmol/L,術后2 d、5 d、10 d CER[(0.27±0.02)g/L、(0.22±0.03)g/L、(0.37±0.05)g/L)]、TRF[(2.85±0.22)g/L、(2.61±0.17)g/L、(3.36±0.05)g/L)]、PA[(243.17±19.86)mg/L、(235.85±19.22)mg/L、(257.81±23.18)mg/L)]高于對照組2 d、5 d、10 d CER[(0.21±0.02)g/L、(0.15±0.02)g/L、(0.25±0.02)g/L)]、TRF[(2.31±0.16)g/L、(2.16±0.15)g/L、(3.02±0.22)g/L)]、PA[(225.46±18.31)mg/L、(210.03±16.32)mg/L、(234.25±20.06)mg/L)](P<0.05)。組間術前胃腸功能指標差異無統計學意義(P>0.05),研究組術后2 d、5 d、10 d VIP低于對照組,GAS、CCK高于對照組(P<0.05)。結論 與開腹手術比較,腹腔鏡結直腸癌根治術治療結直腸癌疾病更為適合,此方式對患者圍術期脂代謝、胃腸功能、蛋白代謝等指標的影響較小,有利于術后康復。
[關鍵詞] 結直腸癌;腹腔鏡;開腹手術;結直腸癌根治術;圍術期
[中圖分類號] R735.3 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1674-0742(2020)01(c)-0016-04
Effect of Laparoscopic Radical Resection of Colorectal Cancer on Body Metabolism and Gastrointestinal Function during Perioperative Period
XU Zhong
Department of General Surgery, Haixiya Hospital of Shanxian County, Heze, Shandong Province, 274300, China
[Abstract] Objective To analyze and discuss the effect of laparoscopic radical resection of colorectal cancer on metabolism and gastrointestinal function during perioperative period. Methods 92 patients with colorectal cancer admitted to the hospital from January 2018 to January 2019 were randomly selected for discussion. They were divided into study group (46 cases of laparoscopic radical resection of colorectal cancer) and control group (46 cases of open surgery). The treatment status, such as perioperative gastrointestinal function, lipid metabolism and protein metabolism, were observed and compared. Results There was not statistically signifiant difference in preoperative lipid metabolism and protein metabolism indexes before surgery(P>0.05). The LDL-C of the study group was lower at 2 d (1.46±0.12) mmol/L, 5 d (1.31±0.12) mmol/L, and 10 d (2.31±0.22) mmol/L better than the control group (1.71±0.15) mmol/L, (1.64±0.14) mmol/L, and (1.88±0.16) mmol/L. At 2 d, TC (2.98±0.21) mmol/L, TG (0.94±0.08) mmol/L, 5 d, TC (2.62±0.18) mmol/L, TG (0.88±0.07) mmol/L, TG (0.82±0.06) mmol/L, 5 d, TC (2.15±0.14) mmol/L, TG (0.71±0.04) mmol/L, Postoperative CER[ (0.27±0.02) g/L, (0.22±0.03) g/L, (0.37±0.05)g/L], TRF [(2.85±0.22) g/L, TRF (2.61±0.17) g/L, (3.36±0.05) g/L], PA[ (243.17±19.86) mg/L, (235.85±19.22) mg/L, (257.81±23.18) mg/L] at 2 d, 5 d and 10 d were higher than those in the control group[ CER(0.21±0.02) g/L, (0.15±0.02) g/L, (0.25±0.02) g/L)], TRF[(2.31±0.16) g/L, (2.16±0.15) g/L, (3.02±0.22) g/L], PA [(225.46±18.31) mg/L, (210.03±16.32) mg/L, (234.25 ±20.06) mg/L](P<0.05). There was not statistically significant difference in preoperative gastrointestinal function indexes between groups(P>0.05). At 2 d, 5 d and 10 d after surgery, the VIP of the study group was lower than that of the control group, and GAS and CCK were higher than that of the control group (P<0.05). Conclusion Compared with open surgery, laparoscopic radical resection of colorectal cancer is more suitable for the treatment of colorectal cancer. This method has less influence on perioperative lipid metabolism, gastrointestinal function, protein metabolism and other indicators
綜上所述,與開腹手術比較,腹腔鏡結直腸癌根治術治療結直腸癌疾病更為適合,此方式對患者圍術期脂代謝、胃腸功能、蛋白代謝等指標的影響較小,有利于術后康復。
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(收稿日期:2019-10-23)