樂映川


【摘要】 目的:探討輸尿管鏡下鈥激光碎石術對輸尿管結石患者術后康復及結石排凈率的影響。方法:選取2018年2月-2019年7月筆者所在醫院收治的輸尿管結石患者115例,依照奇偶順序分為研究組(58例)、對照組(57例)。對照組采用輸尿管鏡氣壓彈道碎石術治療,研究組采用輸尿管鏡下鈥激光碎石術治療。比較兩組手術指標(手術時間、術后血尿持續時間、住院時間)、結石排凈率、并發癥發生率、應激指標(血清皮質醇、丙二醛水平)。結果:研究組結石排凈率為96.55%,高于對照組的75.44%,差異有統計學意義(P<0.05);研究組手術時間、術后血尿持續時間、住院時間均短于對照組,差異均有統計學意義(P<0.05);術后10 min研究組血清皮質醇、丙二醛水平均低于對照組,差異均有統計學意義(P<0.05);研究組術后并發癥發生率為3.45%,低于對照組的17.54%,差異有統計學意義(P<0.05)。結論:輸尿管結石患者采用輸尿管鏡下鈥激光碎石術治療,能縮短手術時間,清除結石,減輕應激反應,促進患者早期康復,安全性高。
【關鍵詞】 輸尿管鏡 鈥激光碎石術 輸尿管結石
doi:10.14033/j.cnki.cfmr.2020.15.010 文獻標識碼 B 文章編號 1674-6805(2020)15-00-03
Effect of Holmium Laser Lithotripsy under Ureteroscope on Postoperative Recovery and Stone Removal Rate of Patients with Ureteral Calculi/LE Yingchuan. //Chinese and Foreign Medical Research, 2020, 18(15): -26
[Abstract] Objective: To investigate the effect of holmium laser lithotripsy under ureteroscope on postoperative recovery and stone removal rate of patients with ureteral calculi. Method: From February 2018 to July 2019, 115 patients with ureteral calculi in our hospital were selected and divided into the study group (58 cases) and the control group (57 cases) according to parity order. The control group was treated with ureteroscopy pneumatic lithotripsy, while the study group was treated with ureteroscopy holmium laser lithotripsy. The surgical indexes (duration of operation, duration of postoperative hematuria, length of hospital stay), stone removal rate, incidence of complications, and stress indexes (serum cortisol and malondialdehyde levels) of two groups were compared. Result: The stone removal rate of the study group was 96.55%, higher than that of the control group (75.44%), the difference was statistically significant (P<0.05). All the operative time, postoperative hematuria duration time and hospital stay time in the study group were shorter than those in the control group, the differences were statistically significant (P<0.05). At 10 minutes after operation, the serum cortisol and malondialdehyde levels in the study group were lower than those in the control group, the differences were statistically significant (P<0.05). The incidence of postoperative complications in the study group was 3.45%, lower than that in the control group (17.54%), the difference was statistically significant (P<0.05). Conclusion: Holmium laser lithotripsy under ureteroscope can shorten the operation time, clear the calculi, reduce the stress response, promote the early recovery of patients with ureteral calculi, with high safety.
皮質醇、丙二醛水平是臨床反映應激反應常見生化指標,其水平越高表明機體應激損傷程度越高[12]。本研究顯示,術后10 min研究組血清皮質醇、丙二醛水平均低于對照組(P<0.05),表明輸尿管結石患者采用輸尿管鏡下鈥激光碎石術治療,能減輕應激反應。此外,輸尿管鏡下鈥激光碎石術對術者專業技術要求較高,其應熟練掌握輸尿管鏡及鈥激光操作技巧,動作輕柔,以減少對輸尿管及其他組織損失,保證手術效果;同時在采用輸尿管鏡查探管腔時,若出現視野受限,未能完全看清整個管腔時,應退出輸尿管鏡,適當調整角度,再繼續前進查探病灶情況;操作時應確保降低膀胱內壓,充分麻醉,以防出現輸尿管抱鏡現象,輸尿管退鏡困難,導致發生輸尿管損傷。
綜上可知,輸尿管結石患者采用輸尿管鏡下鈥激光碎石術治療,能縮短手術時間,清除結石,減輕應激反應,促進患者早期康復,安全性高。
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(收稿日期:2020-01-17) (本文編輯:馬竹君)