中西醫結合治療冠心病36例臨床觀察

魏星 常勇

【摘 要】 目的：觀察中西醫結合治療對冠心病穩定型心絞痛患者的運動耐量和心肌缺血的影響。方法：將73例穩定型心絞痛患者隨機分為2組，對照組37例，觀察組36例。對照組予冠心病常規西藥治療，觀察組在對照組基礎上加用諾迪康膠囊，治療周期均為8周。治療前后兩組均完善心電圖及運動平板實驗，觀察并記錄相關指標。結果：治療8周后，在改善心肌缺血方面，兩組治療后心電圖缺血導聯ST壓低水平均較治療前減低，且觀察組優于對照組，差異有統計學意義（P<0.05），在改善運動耐量方面，治療后觀察組運動時間明顯長于對照組（P<0.05）。結論：中西醫結合治療在改善冠心病穩定型心絞痛患者的心肌缺血、提高運動耐量方面療效較好。

【關鍵詞】 穩定型心絞痛;諾迪康;運動耐量;心肌缺血

【中圖分類號】R541.4? ?【文獻標志碼】 A? ? 【文章編號】1007-8517（2020）9-0106-04

Clinical observation of 36 cases of coronary heart disease treated by integrated Chinese and western medicine

WEI Xing CHANG Yong*

Guangzhou Hospital of Traditional Chinese Medicine，Guangzhou 510000，China

Abstract：ObjectiveTo observe the effects of Nuo Di kang on myocardial ischemia and motion-endurance of the patients with stable angina.MethodsSeventy - three patients with stable angina? were randomly divided into two groups：The control group have 37 patients and the observation group have 36 patients. The control group to the coronary heart disease （CHD） conventional western medicine treatment; On the basis of control group and observation group with di kang capsule， treatment period for 8 week. both groups need to performed the Electrocardiogram and treadmill exercise test before and after treatment. Observe and record the related indexes. ResultsAfter 8 weeks of treatment， the level of ST depression of ECG in the two groups was lower than that before treatment， the observation group was better than the control group in clinical efficacy， the difference between the two groups has statistically significant （P<0.05），In terms of improving exercise tolerance， the exercise time in the observation group after treatment was significantly longer than that in the control group（P<0.05）. ConclusionNuo Di kang Capsule is safe and effective in improving myocardial ischemia and improving exercise tolerance in patients with stable angina.

Key words：stable angina;Nuo Di Kang; motion-endurance;Myocardial Ischemia

冠心病（coronary atherosclerotic heart disease，CHD）是指冠狀動脈（冠脈）發生粥樣硬化引起管腔狹窄或閉塞，導致心肌缺血缺氧或者壞死而引起的心臟病，也稱缺血性心臟病[1]。近年來其發病率不斷增高，已成為中老年患者的主要致死因素，嚴重威脅人類的健康。因此探索冠心病的防治方法，已成為臨床研究熱點之一。純中藥制劑諾迪康，主要原料為紅景天，主要成分為紅景天苷、黃酮等，大量動物及人體試驗研究證實諾迪康有擴張冠脈、調脂、改善心肌缺血缺氧、降低血液黏度、保護神經細胞等作用，現已廣泛應用于心腦血管疾病的防治，且安全性佳[2]。本研究應用常規西藥聯合諾迪康膠囊治療冠心病穩定型心絞痛，觀察其對穩定型心絞痛患者運動耐量及心肌缺血的影響，現報道如下。

1 資料與方法

1.1 一般資料 觀察病例為廣州市中醫醫院2017年1月至2018年10月門診及住院患者，診斷為：冠心病穩定型心絞痛，證屬氣虛血瘀者。……