306例急性腦梗死患者臨床治療效果分析

王紅

[摘要] 目的 探討藥物波立維（氯毗格雷）聯合藥物阿司匹林用于治療急性腦梗死患者的臨床效果。方法 選取該院自2012年10月—2014年9月該院收治的急性腦梗死患者共306例，將其隨機平均分為對照組和觀察組各為153例，對照組給予藥物奧扎格雷鈉靜脈滴注，觀察組給予藥物氯毗格雷片聯合阿司匹林片，14 d為1個療程，然后觀察經過治療后該兩組患者的臨床治療效果。結果 經過1個療程的治療，兩組患者的神經功能缺損評分均比治療前均有所下降，但是以觀察組患者下降幅度為（9.0±7.3）分，明顯優于對照組患者，該兩組的患者的神經功能缺損評分比較，差異有統計學的意義（t=2.81，P<0.05）；觀察組患者的總有效率為86.93%，明顯高于對照組（68.63%），該兩組患者的總有效率對比，差異有統計學意義（P<0.05）。結論 采用藥物波立維（氯毗格雷）聯用藥物阿司匹林，共同治療急性腦梗死患者不但治療效果顯著，而且安全可靠，值得臨床推廣。

[關鍵詞] 急性腦梗死；阿司匹林；氯毗格雷

[中圖分類號] R743.33 [文獻標識碼] A [文章編號] 1674-0742（2015）05（a）-0027-02

Analysis of 306 Cases of Clinical Therapeutic Effect inPatients with Acute Cerebral Infarction

WANG Hong

Internal Medicine-Neurology， The people's Hospital of Huadian City，Jilin Province，132400 China

[Abstract] Objective To investigate the drug Plavix （CL PI Gray） combined with aspirin for clinical effect in the treatment of acute cerebral infarction. Methods In our hospital in patients with acute cerebral infarction from 2012 October to 2014 September in our hospital were a total of 306 cases， which were randomly divided into control group and observation group each 153 cases， the control group was given drug ozagrel sodium intravenous drip， the observation group was given the drug chlorine PI Gray tablets combined with aspirin tablets， 14 days for 1 a course of treatment， and then observed after treatment of the two groups of patients with clinical curative effect. Results After 1 courses of treatment， two groups of patients with neurological deficit scores were compared with those before treatment were decreased， but in the observation group were decreased by （9+7.3）， significantly better than the control group of patients， comparing the two groups of patients with neurologic impairment score， the difference was statistically significant （t=2.81， P <0.05）； patients in the observation group the total effective rate was 86.93%， significantly higher than the control group （68.63%）， the total efficiency compared two groups of patients， it has obvious difference （P<0.05）， there is statistical significance. Conclusion Using drug Plavix （CL PI Gray） combined with aspirin， a common treatment in patients with acute cerebral infarction is not only a significant treatment effect， and is safe and reliable， worthy of clinical application.

[Key words] Acute cerebral infarction； Aspirin； Chlorine PI Gray

腦梗死又稱為缺血性腦卒中，是指由多種因素所導致腦部的血液供應出現障礙，造成患者腦組織缺血或者缺氧性的壞死，從而產生相應神經的功能缺損[1]。對于急性腦梗死患者應用藥物尿激酶溶栓需要在其發病后6 h內進行，而大部分患者在就診的時候已經錯過了溶栓最佳時間[2]。為探討藥物波立維（氯毗格雷）聯合藥物阿司匹林用于治療急性腦梗死患者的臨床效果，在2013年6月—2014年5月期間，該院采用藥物氯毗格雷聯用阿司匹林方案治療153例急性腦梗死患者，并與同期單獨采用藥物奧扎格雷治療的153例患者的療效進行對比觀察，取得了較為滿意的效果，現報道如下。

1 資料與方法

1.1 一般資料

該研究整群選……