何磊 金輝 吳留廣 朱草原

[摘要] 目的 探究腸道營養支持在食管癌術后吻合口瘺的應用意義。方法 將68例食管癌術后并發頸部吻合口瘺患者隨機分成兩組,對照組接受腸外營養支持治療,實驗組實施腸內營養支持治療,對比兩組臨床治療效果。結果 實驗組呼吸道感染發生率(17.65% vs 41.18%)明顯低于對照組(P<0.05),瘺愈合后第1天血清轉鐵蛋白(2.45±0.20)g/L vs (1.97±0.10)g/L顯著高于對照組(P<0.05)。結論 腸內營養支持療法可提升食管癌術后并發頸部吻合口瘺患者機體蛋白合成,維護其肝臟功能。
[關鍵詞] 腸道營養支持;食管癌;食管胃吻合口瘺
[中圖分類號] R735.1 [文獻標識碼] A [文章編號] 1674-0742(2015)05(a)-0042-02
Application of Enteral Nutrition Support in Anastomotic Fistula in Postoperative Esophageal Carcinoma
HE Lei,JIN Hui,WU Liu-guang,ZHU Cao-yuan
Department of emergency, people's hospital of Zhengzhou,Zhengzhou, Henan Province, 450000 China
[Abstract] Objective To explore the significance of application of enteral nutrition support in the anastomotic fistula in postoperative esophageal carcinoma. Methods 68 cases of postoperative complication of cervical anastomotic fistula in esophageal cancer after resection were randomly divided into two groups, the control group received parenteral nutrition support treatment, the experimental group underwent enteral nutrition support treatment, compared clinical curative effect of two groups. Results The incidence of respiratory tract infection in experimental group (17.65% vs 41.18%) was significantly lower than that of control group (P<0.05), fistula healing after 1d of serum transferrin(2.45±0.20)g/L vs (1.97±0.10)g/L was significantly higher than that in control group (P<0.05). Conclusion Enteral nutrition support therapy can improve the postoperative esophageal cancer complicated with cervical anastomotic fistula patients body protein synthesis, maintain the function of liver.
[Key words] Enteral nutrition; Esophageal cancer; Esophagus stomach anastomotic fistula
研究證實,食管癌切除胃食管頸部吻合術時間長、創傷大、術后并發癥較多,尤其易出現頸部吻合口瘺,往往容易影響患者預后。目前,在臨床上,吻合口瘺可經換藥及抗炎、營養支持治療多愈合,常規全腸外營養支持治療中營養要素不完整,阻滯機體免疫功能存在缺陷,而腸內營養支持治療可彌補這一缺陷[1]。為了深入探究腸道營養支持在食管癌術后吻合口瘺的應用意義,該研究主要對2012年6月—2014年9月間該院收治的68例食管癌術后并發頸部吻合口瘺的患者進行平行對照研究,相關報道如下。
1 資料與方法
1.1 一般資料
整群選擇該院收治的食管癌術后并發頸部吻合口瘺的患者68例為研究對象,嚴重肝、心、呼吸等功能紊亂者及感染、免疫系統疾病者,應用完全隨機數字表法,將其隨機分成兩組,例數比值為1:1,其中對照組男性22例,女性12例,平均年齡在(57.16±2.17)歲之間。實驗組男性23例,女性11例,平均(58.35±2.46)歲。兩組患者基數資料對比差異無統計學意義(P>0.05),具有可比性。
1.2 方法
實驗組術中將CHl2-120 cm鼻空腸管放……