慢性萎縮性胃炎患者消化內科臨床治療分析

劉欣

[摘要] 目的 探討消化內科慢性萎縮性胃炎臨床治療方法及效果。 方法 隨機選取慢性萎縮性胃炎80例，均為該院消化內科2013年1月—2014年1月收治，隨機分組，就養胃沖劑單用（對照組，n=40）與加用枸櫞酸鉍鉀、阿莫西林、克拉霉素三聯療法（觀察組，n=40）效果進行比較。 結果 觀察組選取病例經統計示臨床總有效率為92.5%，對照組經統計示為62.5%，兩組比較差異有統計學意義（χ2=8.924，P=0.017）；觀察組患者中發生1例嘔吐和1例消化不良，對照組患者中發生3例嘔吐、3例惡心以及4例消化不良，觀察患者不良反應發生率明顯低于對照組，兩組比較差異有統計學意義（χ2=4.8039，P=0.2840）。 結論 依據慢性萎縮性炎患者臨床特點，在明確診斷的基礎上，取枸櫞酸鉍鉀、阿莫西林、克拉霉素三聯療法應用，可使臨床效果顯著增強，安全性居較高水平，顯著改善疾病預后，使患者生存質量在一定程度上改善，在臨床有較高的應用價值，值得廣泛推廣。

[關鍵詞] 慢性萎縮性胃炎；消化內科；治療分析

[中圖分類號] R59 [文獻標識碼] A [文章編號] 1674-0742（2015）05（b）-0017-02

Analysis of Clinical Treatment for Patients with Chronic Atrophic Gastritis Digestion in Department of Internal Medicine

LIU Xin

Department of Gastroenterology， General Hospital of Hebi Coal Group， Hebi， Henan Province， 458000 China

[Abstract] Objective To investigate clinical treatment for patients with chronic atrophic gastritis digestion in Department of Internal Medicine. Methods 80 patients with chronic atrophic gastritis admitted to the Department of Gastroenterology of our hospital from January 2013 to January 2014 were randomly divided into control group （n=40）and observation group（n=40）. Yangwei Medicinal Instant Granules was used in the control group， while the bismuth potassium citrate ，amoxicillin and clarithromycin triple therapy was additionally used in the observation group. The effect was compared between the two groups. Results The statistical processing revealed that clinical efficacy rate of the observation group was 92.5% and that of the control group was 62.5%， and the difference was statistically significant（χ2=8.924，P=0.017）；There were 1 cases of vomiting， 1 cases of indigestion in the observation group and 1 cases of vomiting， 3 cases of nausea and 4 cases of indigestion in the control group， and the difference was statistically significant（χ2=4.8039，P=0.2840）. Conclusion Based on the clinical features of patients with chronic atrophic inflammation and clear diagnosis， the bismuth potassium citrate， amoxicillin， clarithromycin triple therapy can significantly enhance the clinical effects and significantly improve prognosis of the disease safety. With higher safety and clinical application value， it can also improve the quality of life of patients to some extent， so it is deserves widespread recommendation.

[Key words] Chronic atrophic gastritis； Department of Gastroenterology； Analysis of efficacy

慢性萎縮性胃炎多由動脈硬化、胃血流量不足、嗜好煙酒等因素對胃黏膜屏障功能構成損傷所致，屬消化內科胃部疾病常見類型[1]。萎縮性胃炎時，胃黏膜被腸的上皮細胞取代，即腸化生形成，臨床以上腹飽脹、噯氣、胃納減退等為主要表現，隨病情進屬，癌變比率明顯增加，故對患者生命安全及生存質量構成了嚴重影響[2]。為探討消化內科慢性萎縮性胃炎臨床治療方法及效果。該研究2013年1月—2014年1月間選取相關病例，就養胃沖劑單用，與加用枸櫞酸鉍鉀、阿莫西林、克拉霉素三聯療法效果展開比較，現報道如下。……