余杭區(qū)前列腺增生患病現(xiàn)狀及相關(guān)治療的調(diào)查

高岑 高志朝 彭福生

【摘要】目的：探討杭州市余杭區(qū)前列腺增生的患病現(xiàn)狀及相關(guān)治療情況。方法：選擇浙江省杭州市余杭區(qū)10個(gè)社區(qū)580名中老年男性作為調(diào)查對(duì)象，將研究對(duì)象分成不同的年齡組進(jìn)行研究。比較不同年齡段的IPSS評(píng)分、下尿路癥狀評(píng)分及下尿路癥狀的嚴(yán)重程度，對(duì)比不同年齡段的Qmax水平和前列腺體積，同時(shí)根據(jù)不同的診斷標(biāo)準(zhǔn)統(tǒng)計(jì)前列腺增生的患病率，并且調(diào)查相關(guān)的用藥情況。結(jié)果：隨著年齡的上升，男性人群的IPSS評(píng)分也隨之上升，年齡>80歲男性的平均IPSS評(píng)分高達(dá)（15.90±4.73）分；隨著年齡的上升，下尿路癥狀中的尿道梗阻癥狀評(píng)分、膀胱刺激癥狀評(píng)分顯著上升，且下尿路癥狀的嚴(yán)重程度逐漸提高；Qmax水平隨著年齡的上升而降低，且Qmax水平<15 mL/s的比例提高。不同診斷標(biāo)準(zhǔn)下的前列腺增生患病率存在差異性。用藥情況中以5α-還原酶抑制劑類藥物的使用率最高，α-腎上腺素能受體阻滯劑類藥物、中成藥的使用率也較高。結(jié)論：杭州市余杭區(qū)大部分中老年男性群體存在下尿路癥狀，且隨著年齡的上升，下尿路癥狀越明顯、前列腺增長(zhǎng)的患病率越高，相關(guān)的用藥情況基本合理。

【關(guān)鍵詞】前列腺增生；癥狀；用藥情況；調(diào)查

Investigation on the prevalence and related treatment of prostate hyperplasia in Yuhang cityGAO Cen1， GAO Zhizhao1， PENG Fusheng 2. 1. Department of Urology， Yuhang District First Peoples Hospital， Hangzhou 311100， Zhejiang， China； 2. Department of Urology， Huzhou Central Hospital， Huzhou 313003， Zhejiang， China

【Abstract】Objectives： To investigate the prevalence of the disease and associated treatment of the prostate hyperplasia in Yuhang District of Hangzhou City in Zhejiang Province. Methods： 580 middle-aged men in the 10 communities in Yuhang District were selected and divided into different age groups. The IPSS score， lower urinary tract symptom score and lower urinary tract symptoms were compared among different age groups. The levels of Qmax and prostate volume at different ages were compared. At the same time， according to different diagnostic criteria， the prevalence of prostate hyperplasia was analyzed， and investigation was done on relevant drug use. Results： The IPSS score of the male population also increased with age. The average IPSS score of patients with age over 80 was （15.3±6.1）. Along with the age increasing， the symptoms of urethral obstruction and bladder irritation in lower urinary tract symptoms increased significantly. And the lower urinary tract symptoms gradually improved. Qmax level increased by 15 ml/s. The prevalence of prostatic hyperplasia under different diagnostic criteria was different. The use of 5 - reductase inhibitors was the highest， and the use of alpha - adrenergic receptors was also higher. Conclusion： Most elderly male population has the lower urinary tract symptoms in Yuhang District of Hangzhou City in Zhejiang Province. And with the increase of age， the symptoms of urinary tract are more obvious and the incidence of prostate increases. Drug use situation is basically reasonable.

【Key words】Prostatic hyperplasia； Symptoms； Drug use； Survey

【中圖分類號(hào)】R699.8【文獻(xiàn)標(biāo)志碼】A

前列腺增生在中老年男性人群中十分常見[1]，尿頻、排尿困難、尿失禁、勃起功能障礙等[2]癥狀會(huì)對(duì)患者的生活質(zhì)量產(chǎn)生十分大的影響。目前，臨床上對(duì)于前列腺增生的治療主要遵循緩解癥狀、減輕梗阻、預(yù)防泌尿感染的原則。做好前列腺增生的篩查工作，有利于前列腺增生的預(yù)防和早期治療[3]。目前，臨床上普遍將IPSS評(píng)分、下尿路癥狀、尿流率以及前列腺體積作為前列腺增生的診斷標(biāo)準(zhǔn)。然而，現(xiàn)階段我國(guó)對(duì)前列腺增生疾病缺乏完善的調(diào)查，因而不能充分掌握中老年人群前列腺增生患者的相關(guān)癥狀及用藥情況，無(wú)法針對(duì)性地展開干預(yù)。本文對(duì)浙江省杭州市余杭區(qū)前列腺增生患病現(xiàn)狀及相關(guān)治療情況展開了調(diào)查分析。現(xiàn)……