張瑜琪
【摘要】 目的:探究常規血液透析與高通量血液透析在腎病患者中的治療效果。方法:選取筆者所在醫院100例血液透析患者分組研究,對照組采用常規血液透析,研究組采用高通量血液透析,對比兩組血清尿素(Urea)、肌酐(Cr)、β2-微球蛋白(β2-MG)、感染情況。結果:治療前兩組患者Urea、Cr、β2-MG含量比較,差異無統計學意義(P>0.05);治療后研究組Urea、Cr、β2-MG含量明顯下降,優于對照組,差異有統計學意義(P<0.05)。對照組感染率34.00%,高于研究組的16.00%,差異有統計學意義(P<0.05)。結論:高通量血液透析比常規血液透析治療腎病患者更具有優勢,感染率低,安全性高,可推廣應用。
【關鍵詞】 腎病; 常規血液透析; 高通量血液透析
doi:10.14033/j.cnki.cfmr.2017.30.004 文獻標識碼 A 文章編號 1674-6805(2017)30-0008-02
Treatment Effect Analysis of Regular Hemodialysis and High Flux Hemodialysis in Kidney Disease/ZHANG Yu-qi.//Chinese and Foreign Medical Research,2017,15(30):8-9
【Abstract】 Objective:To investigate the effect of conventional hemodialysis and high flux hemodialysis in patients with nephropathy.Method:100 cases of hemodialysis patients were grouped in our hospital,the control group used conventional hemodialysis,the study group used high flux hemodialysis,compared two groups of serum urea(Urea),creatinine(Cr),beta 2-microglobulin (β2-MG),infection.Result:Compared the two groups of patients before treatment of Urea,Cr andβ2-MG contents,there were no significant differences(P>0.05).After treatment,the study group of Urea,Cr,β2-MG content decreased significantly,which were better than those of the control group,the differences were statistically significant(P<0.05).The infection rate of the control group was 34.00%,higher than that in the study group of 14.00%,the difference was statistically significant(P<0.05).Conclusion:High flux hemodialysis has more advantages than conventional hemodialysis treatment for kidney disease patients,the infection rate is low,high safety,and can be applied.
【Key words】 Kidney disease; Conventional hemodialysis; High flux hemodialysis
First-authors address:Xiaogan Central Hospital Affiliated to Wuhan University of Science and Technology,Xiaogan 432100,China
目前腎衰竭患者多采取血液透析治療,可有效清除患者尿毒癥毒素,維持機體水、電解質、酸堿平衡,因而受到臨床高度關注[1-3]。傳統血液透析治療近期效果良好,但隨著治療時間延長,患者體內大分子毒素不斷累積,可能導致肺部感染、高血壓、皮膚瘙癢等并發癥,危害患者健康,降低患者生活質量[4-5]。近期有文獻[6]研究指出,高通量血液透析治療效果良好,且并發癥少,安全性高,因而筆者選取院內收治的100例腎病血液透析患者分組研究其與常規血液透析臨床價值,現報道如下。
1 資料與方法
1.1 一般資料
研究選取筆者所在醫院2016年1月-2017年1月收治的100例血液透析治療的腎病患者作為研究對象,采取隨機數字表法將患者分為研究組與對照組[7],每組50例。所有患者均自愿參與試驗研究,并簽署協議,本次研究經倫理會批準進行。對照組:男25例,女25例;年齡22~77歲,平均(61.24±5.36)歲;
病程14~67個月;血液透析治療時間0.5~5年,平均(1.47±0.23)年。研究組:男26例,女24例;年齡20~79歲,平均(61.21±5.39)歲;病程12~69個月;血液……