健脾降濁化瘀湯治療功能性消化不良40例效果研究

吳樹(shù)信

【摘要】 目的：探究健脾降濁化瘀湯治療功能性消化不良的效果。方法：收集2015年2月-2016年2月筆者所在醫(yī)院門(mén)診收治的80例功能性消化不良患者，隨機(jī)分為兩組，觀(guān)察組予健脾降濁化瘀湯治療，對(duì)照組予常規(guī)西醫(yī)治療，比較兩組治療效果。結(jié)果：治療后觀(guān)察組上腹疼痛、上腹燒灼感、早飽感、餐后飽脹積分顯著低于對(duì)照組；觀(guān)察組治療總有效率高于對(duì)照組；觀(guān)察組血漿胃泌素、胃動(dòng)素以及血漿生長(zhǎng)抑素溶度優(yōu)于對(duì)照組，以上比較差異均有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論：健脾降濁化瘀湯治療功能性消化不良效果顯著，值得臨床推廣。

【關(guān)鍵詞】 健脾降濁化瘀湯； 嗎丁啉； 功能性消化不良

doi：10.14033/j.cnki.cfmr.2017.30.007 文獻(xiàn)標(biāo)識(shí)碼 B 文章編號(hào) 1674-6805（2017）30-0014-02

Clinical Study on 40 Cases of Functional Dyspepsia Treated by Jianpi Jiangzhuo Huayu Decoction/WU Shu-xin.//Chinese and Foreign Medical Research，2017，15（30）：14-15

【Abstract】 Objective：To study the clinical effect of Jianpi Jiangzhuo Huayu Decoction in functional dyspepsia.Method：80 patients with functional dyspepsia from February 2015 to February 2016 were collected and randomly divided into two groups，the observation group was treated with Jianpi Jiangzhuo Huayu Decoction，while the control group was treated with conventional western medicine.The therapeutic effects were compared.Result：After treatment，the upper abdominal pain point，epigastric burning sensation point，early satiety point，postprandial fullness point of the observation group were significantly lower than the control group.The effective rate of the observation group was higher than that of the control group.The plasma gastrin，motilin and plasma somatostatin solubility of the observation group were better than those of the control group.The differences above were statistically significant（P<0.05）.Conclusion：Jianpi Jiangzhuo Huayu decoction has a significant effect on the treatment of functional dyspepsia，which is worthy of clinical promotion.

【Key words】 Jianpi Jiangzhuo Huayu Decoction； Domperidone； Functional dyspepsia

First-authors address：Affiliated Peoples Hospital of Fujian Traditional Chinese Medicine University，F(xiàn)uzhou 350004，China

臨床上，功能性消化不良是發(fā)病率較高的消化系統(tǒng)病癥，該病發(fā)病幾率非常高，臨床癥狀繁多，迄今為止，尚未明確功能性消化不良的發(fā)病機(jī)制，可能與精神因素、飲食因素等密切相關(guān)[1]。常規(guī)西醫(yī)治療方式效果不理想，容易復(fù)發(fā)，遷延難愈，為探究健脾降濁化瘀湯治療功能性消化不良的效果，本文研究如下。

1 資料與方法

1.1 診斷標(biāo)準(zhǔn)

（1）西醫(yī)診斷標(biāo)準(zhǔn)。羅馬Ⅲ診斷：早飽感；餐后飽脹；上腹灼燒；上腹痛，必須符合至少1條癥狀，且無(wú)解釋上述癥狀的器質(zhì)性疾病，出現(xiàn)上述癥狀最少半年[2]。（2）中醫(yī)診斷標(biāo)準(zhǔn)。主證：脘腹痞滿(mǎn)；悶塞不舒；舌體胖大、苔白膩；脈沉滑。次證：身重肢倦；頭暈?zāi)垦＃粣盒膰I吐；口淡不渴[3]。

1.2 納入與排除標(biāo)準(zhǔn)

納入標(biāo)準(zhǔn)：（1）患者均與羅馬Ⅲ診斷標(biāo)準(zhǔn)相吻合、與中醫(yī)辨證依據(jù)相吻合。（2）患者年齡均超過(guò)18歲。（3）經(jīng)倫理學(xué)同意，且患者均知情。排除標(biāo)準(zhǔn)：（1）合并造血系統(tǒng)疾病以及心腎疾病患者。……