朱閩波 陳麗萍

[摘要] 目的 探討宮腔鏡對子宮內膜質量與容受性的相關性及對試管嬰兒成功率的影響。 方法 選取我院2017年6月~2018年3月期間收治的不孕患者80例。將其隨機分成兩組,即研究組和對照組。其中,研究組的患者將采用宮腔鏡子宮內膜微創術進行干預治療;對照組患者予基礎干預治療。對比兩組患者的干預后各指標的結果,進而對比兩組的干預效果。 結果 研究組患者的孕激素表達水平明顯高于對照組(P<0.05);研究組患者的血清性激素略高于對照組(P<0.05);研究組患者試管嬰兒的成功率明顯高于對照組(P<0.05)。 結論 對不孕的患者而言,采取使用宮腔鏡子宮內膜微創術的干預治療方式,可以有效改善患者子宮內膜的環境,促進患者孕激素以及患者血清性激素的分泌,能有效提升患者進行試管嬰兒的成功率。
[關鍵詞] 宮腔鏡;子宮內膜質量;容受性;相關性;試管嬰兒;成功率
[中圖分類號] R713.4? ? ? ? ? [文獻標識碼] B? ? ? ? ? [文章編號] 1673-9701(2019)09-0060-03
[Abstract] Objective To explore the correlation between hysteroscopy and endometrial quality and receptivity and the success rate of IVF. Methods Eighty infertile patients admitted to our hospital from June 2017 to March 2018 were selected. They were randomly divided into two groups, the study group and the control group. Among them, the patients in the study group were treated with hysteroscopic endometrial minimally invasive surgery; the patients in the control group were treated with basic intervention. The results of each index after intervention in the two groups were compared, and the intervention effects of the two groups were compared. Results The progesterone expression level of the study group was significantly higher than that of the control group(P<0.05). The serum sex hormones of the study group were slightly higher than that of the control group(P<0.05). The success rate of test tube infants in the study group was significantly higher than that of the control group(P<0.05). Conclusion For infertile patients, interventional treatment with hysteroscopic endometrial minimally invasive surgery can effectively improve the environment of the patients endometrium, promote the secretion of progesterone and serum hormones in patients, and effectively improve the success rate of IVF.
[Key words] Hysteroscopy; Endometrial quality; Receptivity; Correlation; IVF; Success rate
子宮內膜中允許胚囊附著、侵入以及子宮內部特定部位子宮內膜間質發生變化的特異性改變稱為子宮內膜的容受性[1]。子宮內膜容受性的情況與胚胎的著床情況有密切的關聯,好的子宮內膜容受性將會是胚胎著床的有利條件[2]。現如今,隨著人們生活水平的提高和改善,人們的生活習慣也隨之發生改變,以及人們壓力的不斷的增加[3],導致不孕的發病率在逐年上升。因此,生殖輔助技術得到了廣泛的應用。現如今,宮腔鏡在子宮內膜微創術中具有創傷小、操作方便并且安全性高等的特點,在臨床中使用度較頻繁[4]。本文研究患者采取使用宮腔鏡子宮內膜微創手術對患者子宮內膜容受性的影響以及試管嬰兒的成功率,現報道如下。
1 資料與方法
1.1一般資料
選取我院2017年6月~2018年3月期間收治的不孕患者80例。將其隨機分成兩組,即研究組和對照組。其中,研究組患者40例,年齡23~42歲,平均(31.6±2.3)歲,病程2~8年,平均(4.1±0.9)年;對照組患者40例,年齡22~40歲,平均(30.4±1.9)歲,病程2~7年,平均(3.7±0.8)年。納入標準:患者均經過3次或3次以上的胚胎移植失敗并且患者在3個月內未接受雌孕激素的任何治療。排除標準:排除子宮患有其他疾病者。兩組患者的一般資料具有可比性(P>0.05),并且均知情同意本研究,同時本研究經過醫院倫理委員會批準。