電針風池穴對實驗性偏頭痛大鼠腦血流影響研究

康咪　屈簫簫　邵娣　尹曉航

摘要：目的 觀察電針風池穴對實驗性偏頭痛大鼠行為癥狀學及腦血流的影響。方法 選取合格SD大鼠40只，按體重均衡原則分為4組（對照組、模型組、風池穴電針組、非穴電針組4組），每組10只，雌雄各半。對照組：予正常抓取，不作處理;模型組：參照硝酸甘油型偏頭痛大鼠模型復制方法造模，建模后不予處理;風池穴電針組（造模后大鼠）與非穴電針組（造模后大鼠）均予以電針治療：2 Hz和100 Hz交替，疏密波，刺激時間為10 min，后用TS激光探頭測試大鼠頭部腦血流量（PU值）。結果 針刺后，風池穴電針組與非穴電針組均能降低大鼠耳紅持續時間、前肢撓頭持續時間及大鼠各時間段撓頭次數，具有統計學意義（P<0.05，P<0.01），其中風池穴組優于非穴組，具有統計學意義（P<0.01）;針刺后，風池穴組及非穴組偏頭痛大鼠的腦血流量均升高，且風池穴組明顯優于非穴組，具有統計學意義（P<0.01）。結論 針刺風池穴及非穴均能降低大鼠耳紅持續時間、前肢撓頭持續時間及大鼠各時間段撓頭次數，且風池穴組優于非穴組;針刺后均能有效改善偏頭痛大鼠的腦血流量，風池穴組優于非穴組。

關鍵詞：風池穴;非穴;實驗性偏頭痛;腦血流量

中圖分類號R245.3 文獻標志碼：A 文章編號：1007-2349（2019）05-0070-03

【Abstract】Objective： To observe the effect of electroacupuncture at Fengchi acupoint on behavioral symptomology and cerebral blood flow in experimental migraine rats. Methods： 40 SD rats were selected and divided into 4 groups according to the principle of weight balance （control group， model group， Fengchi acupuncture group， non-acupoint electroacupuncture group ）， 10 rats in each group， half male and half female. The control group were given normal capture and no treatment. The model group was established by reference model of nitroglycerin-type migraine rat model replication and no treatment after modeling. The Fengchi acupuncture group （rats after modeling） and non- electroacupuncture group （rats after modeling） were treated with electroacupuncture， alternating 2Hz and 100Hz with sparse wave， and stimulation time was 10 min， and then the brain blood flow （PU value） of the rat head was tested with TS laser probe. Results： After acupuncture， the rats in the Fengchi acupuncture group and the non-acupoint electroacupuncture group could reduce the duration of ear redness， the duration of forearm scratching and the number of head scratching in each period， which was statistically significant （P<0.05， P<0.01）， in which the Fengchi acupoint group was superior to the non-acupoint group， which was statistically significant （P<0.01）. After acupuncture， the cerebral blood flow of the Fengchi acupoint group and the non-acupoint group migraine rats increased. The Fengchi acupoint group was significantly better than the non-acupoint group， which was statistically significant （P<0.01）. Conclusion： Acupuncture at Fengchi and non-acupoints can reduce the duration of ear redness， the duration of forearm scratching and the number of head scratching in rats. The Fengchi acupoint group is better than non-acupoint group. The electroacupuncture at Fengchi Point can improve the cerebral blood flow in migraine rats after acupuncture and the Fengchi acupoint group was superior to the non-acupoint group.