核醫(yī)學(xué)顯像與多普勒超聲診斷在亞急性甲狀腺炎中的臨床應(yīng)用

粘迪 吳桐

[摘要]目的 探討核醫(yī)學(xué)顯像與多普勒超聲診斷在亞急性甲狀腺炎中的臨床應(yīng)用。方法 選取2011年10月～2013年12月在我院進(jìn)行診治的133例亞急性甲狀腺炎患者與133例非亞急性甲狀腺炎患者作為研究對(duì)象，均行核醫(yī)學(xué)顯像診斷檢查和多普勒超聲診斷檢查。以細(xì)針穿刺細(xì)胞學(xué)檢查結(jié)果作為參照，分析核醫(yī)學(xué)顯像診斷檢查、多普勒超聲診斷檢查及聯(lián)合診斷檢查的臨床診斷價(jià)值（靈敏度、特異度、準(zhǔn)確度、陽(yáng)性預(yù)測(cè)值）。結(jié)果 核醫(yī)學(xué)顯像診斷檢查的靈敏度（80.5%）、特異度（83.5%）、準(zhǔn)確度（82.0%）均高于多普勒超聲診斷檢查（69.2%、71.4%、70.3%），聯(lián)合診斷檢查的靈敏度（98.5%）、特異度（97.7%）、準(zhǔn)確度（98.1%）均高于核醫(yī)學(xué)顯像診斷檢查和多普勒超聲診斷檢查，差異均有統(tǒng)計(jì)學(xué)意義（P<0.05）。多普勒超聲診斷檢查、核醫(yī)學(xué)顯像診斷檢查及聯(lián)合診斷檢查的陽(yáng)性預(yù)測(cè)值比較，差異均無(wú)統(tǒng)計(jì)學(xué)意義（P>0.05）。結(jié)論 核醫(yī)學(xué)顯像診斷檢查與多普勒超聲診斷檢查均是亞急性甲狀腺炎的有效診斷方法，聯(lián)合診斷可提高疾病的診斷率。

[關(guān)鍵詞]核醫(yī)學(xué)顯像;多普勒超聲;診斷檢查;亞急性甲狀腺炎;臨床應(yīng)用價(jià)值

[中圖分類(lèi)號(hào)] R581? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-4721（2020）3（c）-0122-04

Clinical application of nuclear medicine imaging and Doppler ultrasound diagnosis in subacute thyroiditis

NIAN Di1? ?WU Tong2

1. Department of Ultrasound， Fushun Central Hospital， Liaoning Province， Fushun? ?113006， China; 2. Department of Magnetic Resonance， Fushun Central Hospital， Liaoning Province， Fushun? ?113006， China

[Abstract] Objective To investigate clinical application of nuclear medicine imaging and Doppler ultrasound diagnosis in subacute thyroiditis. Methods A total of 133 patients with subacute thyroiditis and 133 patients without subacute thyroiditis treated in hospital from October 2011 to December 2013 were selected， who performed nuclear medicine imaging diagnosis and Doppler ultrasound diagnosis. The results of fine needle aspiration cytology were used as reference. The clinical diagnostic value （sensitivity， specificity， accuracy， positive predictive value） of nuclear medicine imaging diagnostic examination， Doppler ultrasound diagnostic examination and combined diagnostic examination were analyzed. Results The sensitivity （80.5%）， specificity （83.5%） and accuracy （82.0%） of nuclear medical imaging diagnostic examination were higher than those of Doppler ultrasound diagnostic examination （69.2%， 71.4% and 70.3%）， the sensitivity （98.5%）， specificity （97.7%） and accuracy （98.1%） of the combined diagnostic examination were all higher than those of nuclear medical imaging diagnostic examination and Doppler ultrasound diagnostic examination， and the differences were statistically significant （P<0.05）. There was no statistically significant difference in the positive predictive value of Doppler ultrasound diagnostic examination， nuclear medicine imaging diagnostic examination and combined diagnostic examination （P>0.05）. Conclusion Nuclear medicine imaging diagnosis and Doppler ultrasound diagnosis are effective methods in diagnosis of subacute thyroiditis. Combined diagnosis can improve diagnostic rate of diseases.

[Key words] Nuclear medicine imaging; Doppler ultrasound; Diagnosis; Subacute thyroiditis; Clinical application value

亞急性甲狀腺炎，可簡(jiǎn)稱為亞甲炎，是臨床較為常見(jiàn)的一種內(nèi)分泌疾病，在甲狀腺疾病中具有較高的發(fā)病率[1-3]，其臨床表現(xiàn)在早期可呈現(xiàn)多樣化，加之患者的就診時(shí)間不同、個(gè)體表現(xiàn)差異性，容易造成患者延誤最佳的治療時(shí)機(jī)，而影響到患者的預(yù)后狀況。亞急性甲狀腺炎的有效診斷方法為影像學(xué)檢查[4-6]，目前較為常用的影像學(xué)檢查方法為核醫(yī)學(xué)顯像診斷檢查與多普勒超聲診斷檢查。為了探討……