馬亮亮



【摘要】 目的:探討糖尿病合并肺結核患者的營養狀況對肺功能的影響,以為臨床工作提供參考。方法:隨機選取2018年1月-2019年5月在筆者所在醫院住院的137例糖尿病合并肺結核患者,入選患者分別測量體質量指數(BMI)、上臂圍(MAC)和白蛋白(ALB)等營養指標及肺功能。根據身體質量指數(BMI)值分為A1組(≥18.5 kg/m2)和A2組(<18.5 kg/m2);按上臂圍(MAC)值分為B1組(≥24 cm)和B2組(<24 cm);按白蛋白(ALB)值分為C1組(≥35 g/L)和C2組(<35 g/L),分別比較各組肺功能指標,并對BMI、MAC、ALB與肺功能各項指標進行相關性研究。結果:A2組FEV1%低于A1組,RV高于A1組,差異均有統計學意義(P<0.05),兩組FVC%、FEV1/FVC%、MVV%比較差異無統計學意義(P>0.05);B2組FEV1%低于B1組,RV高于B1組,差異均有統計學意義(P<0.05),兩組FVC%、FEV1/FVC%、MVV%比較差異無統計學意義(P>0.05);C2組FEV1%低于C1組,RV高于C1組,差異均有統計學意義(P<0.05),兩組FVC%、FEV1/FVC%、MVV%比較差異無統計學意義(P>0.05)。BMI與FVC%、FEV1%呈正相關(r=0.291、0.477,P=0.001,0.000),與RV呈負相關(r=-0.299,P=0.012);MAC與FVC%、FEV1%、MVV%呈正相關(r=0.302、0.456、0.245,P=0.000、0.000、0.004),與RV呈負相關(r=-0.280,P=0.001);ALB與FVC%、FEV1%、MVV%呈正相關(r=0.266、0.432、0.261,P=0.002、0.000、0.002),與RV呈負相關(r=-0.314,P=0.000)。結論:糖尿病合并肺結核患者的營養狀態與肺功能密切相關,營養不良會影響肺功能,改善患者的營養狀況有助于提高患者呼吸功能指數及預后。
【關鍵詞】 糖尿病 肺結核 體質量指數 上臂圍 白蛋白 肺功能
doi:10.14033/j.cnki.cfmr.2020.12.076 文獻標識碼 B 文章編號 1674-6805(2020)12-0-03
Study on the Correlation between Nutritional Status and Pulmonary Function in Diabetic Patients with Pulmonary Tuberculosis/MA Liangliang. //Chinese and Foreign Medical Research, 2020, 18(12): -182
[Abstract] Objective: To explore the influence of nutritional status on pulmonary function in patients with diabetes mellitus complicated with tuberculosis, so as to provide reference for clinical work. Method: A total of 137 patients with diabetes mellitus and tuberculosis who were hospitalized in my hospital from January 2018 to May 2019 were randomly selected. They were investigated by body mass index (BMI), upper arm circumference (MAC) and albumin (ALB) and assessed by lung function. They were divided into A1 group (≥18.5 kg/m2) and A2 group (<18.5 kg/m2) according to BMI value, B1 group (≥24 cm) and B2 group (<24 cm) according to MAC, C1 group (≥35 g/L) and C2 group (<35 g/L) according to ALB value. The differences of pulmonary function indices were compared among each group, and the correlation between BMI, MAC, ALB and pulmonary function indices was analyzed. Result: The FEV1% of A2 group was lower than that of A1 group, the RV was higher than that of A1 group (P<0.05), there was no significant difference in FVC%, FEV1/FVC%, MVV% between the two groups (P>0.05). The FEV1% of B2 group was lower than that of B1 group, the RV was higher than that of B1 group (P<0.05), there was no significant difference in FVC%, FEV1/FVC%, MVV% between the two groups (P>0.05). The FEV1% of C2 group was lower than that of C1 group, the RV was higher than that of C1 group (P<0.05), there was no significant difference in FVC%, FEV1/FVC%, MVV% between the two groups (P>0.05). BMI were positively correlated with FVC%, FEV1% (r=0.291, 0.477, P=0.001, 0.000), and was negatively correlated with RV (r=-0.299, P=0.012). MAC was positively correlated with FVC%, FEV1% and MVV% (r=0.302, 0.456, 0.245, P= 0.000, 0.000, 0.004), and was negatively correlated with RV (r=- 0.280, P=0.001). ALB was positively correlated with FVC%, FEV1% and MVV (r=0.266, 0.432, 0.261, P=0.002, 0.000, 0.002), and was negatively correlated with RV (r=-0.314, P=0.000). Conclusion: The nutritional status of diabetic patients with pulmonary tuberculosis is closely related to pulmonary function. Malnutrition will affect pulmonary function. Improving the nutritional status of patients will help to improve the respiratory function index and prognosis.
[Key words] Diabetes mellitus Pulmonary tuberculosis Body mass index Upper arm circumference Albumin Lung function
First-authors address: Beijing Geriatric Hospital, Beijing 100095, China
糖尿病和結核病是我國常見的慢性病,糖尿病患者肺結核患病率是普通人群的3~4倍[1]。糖尿病合并肺結核,兩病相互影響,相互促進,在臨床上較為常見,且有逐年增長的趨勢[2-3]。糖尿病是結核病的易感因素,肺結核是一種與營養不良有關的疾病,這兩種病都是慢性消耗性疾病,營養不良發生率相對較高。肺功能作為判斷病情嚴重性和預后的重要參考指標,常用于評估呼吸系統疾病患者的病情。本文主要探討糖尿病合并肺結核患者營養狀況對肺功能的影響,為臨床營養治療提供理論參考,具體如下。
1 資料與方法
1.1 一般資料
收集2018年1月-2019年5月在筆者所在醫院住院并確診的糖尿病合并肺結核患者137例。……