經(jīng)皮射頻消融術(shù)與腹腔鏡肝癌切除術(shù)治療小肝癌的臨床效果比較

譚立業(yè) 汪晶 肖陽(yáng) 夏玲洋

[摘要]目的 比較經(jīng)皮射頻消融術(shù)與腹腔鏡肝癌切除術(shù)治療小肝癌的臨床效果。方法? 選取2016年2月～2018年2月我院收治的100例小肝癌患者作為研究對(duì)象，按照入院順序方法分為觀察組（50例）與對(duì)照組（50例）。觀察組采用經(jīng)皮射頻消融術(shù)治療方法，對(duì)照組采用腹腔鏡肝癌切除術(shù)治療方法。比較兩組的肝功能指標(biāo)、并發(fā)癥情況、生存時(shí)間和無(wú)瘤生存時(shí)間。結(jié)果 觀察組治療后的丙氨酸氨基轉(zhuǎn)移酶（ALT）、天門(mén)冬氨酸氨基轉(zhuǎn)移酶（AST）水平低于對(duì)照組，差異均有統(tǒng)計(jì)學(xué)意義（P<0.05）;觀察組的并發(fā)癥總發(fā)生率低于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）;觀察組的生存時(shí)間和無(wú)瘤生存時(shí)間長(zhǎng)于對(duì)照組，差異均有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論 經(jīng)皮射頻消融術(shù)治療小肝癌效果顯著，且能夠降低其并發(fā)癥發(fā)生率，延長(zhǎng)患者生存時(shí)間，改善患者肝功能。

[關(guān)鍵詞]經(jīng)皮射頻消融術(shù);腹腔鏡肝癌切除術(shù);小肝癌;臨床效果

[中圖分類(lèi)號(hào)] R735.7? ? ? ? ? [文獻(xiàn)標(biāo)識(shí)碼] A? ? ? ? ? [文章編號(hào)] 1674-4721（2020）5（b）-0096-03

Comparison of clinical effects between percutaneous radiofrequency ablation and laparoscopic liver cancer resection in the treatment of small hepatocellular carcinoma

TAN Li-ye1? ?WANG Jing2? ?XIAO Yang1? ?XIA Ling-yang3▲

1. Department of Hepatobiliary Surgery， the Second Affiliated Hospital of Mudanjiang Medical University， Heilongjiang Province， Mudanjiang? ?157000， China; 2. Department of Cardiology， the Second Affiliated Hospital of Mudanjiang Medical University， Heilongjiang Province， Mudanjiang? ?157000， China; 3. Department of Neurosurgery， the Second Affiliated Hospital of Mudanjiang Medical University， Heilongjiang Province， Mudanjiang? ?157000， China

[Abstract] Objective To compare the clinical effect of percutaneous radiofrequency ablation and laparoscopic liver cancer resection in the treatment of small hepatocellular carcinoma. Methods A total of 100 patients with small hepatocellular carcinoma admitted to our hospital from February 2016 to February 2018 were selected as study objects. They were divided into the observation group （n=50） and the control group （n=50） according to the order of admission. In the observation group， percutaneous radiofrequency ablation was used， while in the control group， laparoscopic liver resection was adopted. Liver function indexes， complications， survival time， and tumor-free survival time were compared between the two groups. Results The levels of alanine aminotransferase （ALT） and aspartate aminotransferase （AST） in the observation group after treatment were lower than those in the control group， and the differences were statistically significant （P<0.05）. The total incidence of complications in the observation group was lower than that of the control group， and the difference was statistically significant （P<0.05）. The survival time and tumor-free survival time of the observation group were longer than those of the control group， with statistical differences （P<0.05）. Conclusion Percutaneous radiofrequency ablation is effective in treating small hepatocellular carcinoma， and can reduce the incidence of complications， prolong the survival time of patients， and improve liver function.