醒腦靜注射液治療急性重癥腦血管病的臨床療效

王福星

摘要：目的 ?觀察醒腦靜注射液治療急性重癥腦血管病的臨床療效。方法 ?選取2018年7月～2019年7月在我院診治的134例急性重癥腦血管病患者為研究對象，采用隨機數字表法分為對照組和觀察組，各67例。對照組采用常規治療，觀察組在對照組基礎上采用醒腦靜注射液治療，比較兩組臨床治療總有效率、神經功能缺損評分、格拉斯哥昏迷（GCS）評分及臨床不良反應發生情況。結果 ?觀察組臨床治療總有效率為94.02%，高于對照組的80.59%（P<0.05）;治療后兩組神經功能缺損評分均低于治療前，且觀察組低于對照組（P<0.05）;治療后兩組GCS評分均低于治療前，且觀察組低于對照組（P<0.05）;觀察組臨床不良反應發生率與對照組比較，差異無統計學意義（P>0.05）。結論 ?醒腦靜注射液治療急性重癥腦血管病療效顯著，總有效率高，可顯著改善患者神經功能缺損，降低GCS評分，且臨床不良反應少。

關鍵詞：醒腦靜注射液;神經功能缺損;腦血管病

中圖分類號：R971 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 文獻標識碼：A ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? DOI：10.3969/j.issn.1006-1959.2020.18.054

文章編號：1006-1959（2020）18-0162-02

Clinical Observation of Xingnaojing Injection in the Treatment

of Acute Severe Cerebrovascular Disease

WANG Fu-xing

（Department of Neurosurgery，Dongli Hospital，Dongli District，Tianjin 300300，China）

Abstract：Objective ?To observe the clinical efficacy of Xingnaojing injection in the treatment of acute severe cerebrovascular disease.Methods ?A total of 134 patients with acute severe cerebrovascular disease diagnosed and treated in our hospital from July 2018 to July 2019 were selected as the research objects. They were divided into control group and observation group by random number table method， with 67 cases in each group. The control group was treated with conventional treatment， and the observation group was treated with Xingnaojing injection on the basis of the control group. The total effective rate of clinical treatment， neurological deficit score， Glasgow coma （GCS） score and the occurrence of clinical adverse reactions were compared between the two groups.Results ?The total effective rate of clinical treatment in the observation group was 94.02%， which was higher than 80.59% in the control group（P<0.05）; the scores of neurological deficits in the two groups after treatment were lower than those before treatment， and the observation group was lower in the control group（P<0.05）; after treatment， the GCS scores of the two groups were lower than before treatment， and the observation group was lower than the control group（P<0.05）; clinical adverse reactions in the observation group compared with the control group， the incidence rate was not statistically significant （P>0.05）.Conclusion ?Xingnaojing injection had a significant curative effect in the treatment of acute severe cerebrovascular disease. The total effective rate was high. It could significantly improve patients' neurological deficits， reduce GCS scores， and had fewer clinical adverse reactions.

Key words：Xingnaojing injection;Neurological deficit;Cerebrovascular disease

急性重癥腦血管疾病屬于急性多發病，分為缺血性、出血性、高血壓等情況，主要由于腦組織短時間內缺血、缺氧，造成腦細胞水腫、顱內壓升高，進一步使神經系統受損。目前常規給予利尿劑、脫水劑等綜合治療，雖可控制患者病情，但治療效果不佳。中醫藥在活血祛瘀方面有標本兼治之功效，醒腦靜注射液屬于中藥復方制劑，有明顯抗炎、改善微循環、消除水腫、改善神經功能等作用，在治療急性重癥腦血管疾病方面具有一定的優勢，但臨床應用情況尚未完全明確，有待進一步研究[1]。本研究結合2018年7月～2019年7月在我院診治的134例急性重癥腦血管病患者臨床資料，研究醒腦靜注射液治療急性重癥腦血管病臨床效果，現報道如下?！?br>