“特殊生態環境微生物及次級代謝產物”專輯特邀主編孫承航研究員簡介

孫承航，男，1966年7月出生，中國醫學科學院北京協和醫學院醫藥生物研究所研究員，博士研究生導師，微生物化學研究室主任。1999年于中國醫學科學院&中國協和醫科大學獲博士學位。以海外研究員和博士后身份，先后在日本北里研究所和約翰霍普金斯大學公共衛生學院從事抗感染相關研究。研究領域：特殊生態環境藥用微生物資源勘探和新抗生素發現，具體包括：特殊生態環境放線菌多樣性及新穎性研究、放線菌物種鑒定、基于色譜-質譜聯用分子網絡發現新抗生素、化合物分離純化與結構鑒定。先后主持“十一五”和“十二五”國家科技重大專項、重大新藥創制課題“微生物產物化學研究”和“特境微生物創新藥物研究”，中國醫學科學院醫學與健康科技創新工程服務“一帶一路”戰略先導科研專項“特殊環境中藥用微生物資源發現與利用”，多項國家自然科學基金以及國際合作課題。特境來源藥用微生物資源勘探和新抗生素發現代表作如下(*為通訊作者)：

沙漠特境：

1.Shao-wei Liu,Norovsuren Jadambaa,Arina A.Nikandrova,Ilya A.Osterman and Cheng-hang Sun*: Exploring the Diversity and Antibacterial Potentiality of Cultivable Actinobacteria from the Soil of the Saxaul Forest in Southern Gobi Desert in Mongolia.Microorganisms 2022,10: 989.https://doi.org/10.3390/microorganisms10050989.

2.Shao-wei Liu,Ting Wang,Qin-pei Lu,Fei-na Li,Gang Wu,Zhong-ke Jiang,Xugela Habden,Lin Liu,Xiao-lin Zhang,Dmitrii A.Lukianov,Ilya A.Osterman,Petr V.Sergiev,Olga A.Dontsova and Cheng-hang Sun*:Bioprospecting of Soil-Derived Actinobacteria along the Alar-Hotan Desert Highway in the Taklamakan Desert.Frontiers in microbiology 2021,12: 604999，https://doi.org/10.3389/fmicb.2021.604999.

3.Wang Ting,Li Feina,Lu Qinpei,Habden Xugela,Razumova Elizaveta A,Osterman Ilya A,Sergiev Petr V,Dontsova Olga A,You Xuefu,Sun Chenghang*: Studies on diversity,novelty,antimicrobial activity and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected in Taklamakan desert.Journal of Pharmaceutical Analysis.2021,11(2): 241-250.https://doi.org/10.1016/j.jpha.2020.06.004.

紅樹林特境：

4.Qin-Pei Lu,Yong-Mei Huang,Shao-Wei Liu,Gang Wu,Qin Yang,Li-Fang Liu,Hai-Tao Zhang,Yi Qi,Ting Wang,Zhong-Ke Jiang,Jun-Jie Li,Hao Cai,Xiu-Jun Liu,Hui Luo*and Cheng-Hang Sun*: Metabolomics Tools Assisting Classic Screening Methods in Discovering New Antibiotics from Mangrove Actinomycetia in Leizhou Peninsula.Marine drugs,2021,19: 688.https://doi.org/10.3390/md19120688.

5.Qin-Pei Lu,Jing-Jing Ye,Yong-Mei Huang,Di Liu,Li-Fang Liu,Kun Dong,Elizaveta Andreevna Razumova,Ilya Andreevich Osterman,Petr Vladimirovich Sergiev,Olga Anatolievna Dontsova,Shu-Han Jia,Da-Lin Huang,Cheng-Hang Sun*: Exploitation of Potentially New Antibiotics from Mangrove Actinobacteria in Maowei Sea by Combination of Multiple Discovery Strategies.Antibiotics 2019,8(4): 36; https://doi.org/10.3390/antibiotics8040236.

6.Jiang Zhong-Ke,Tuo Li,Huang Da-Lin,Osterman Ilya A,Tyurin Anton P,Liu Shao-Wei,Lukyanov Dmitry A,Sergiev Petr V,Dontsova Olga A,Korshun Vladimir A,Li Fei-Na,Sun Cheng-Hang*: Diversity,novelty,and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi,China.Frontiers in Microbiology,2018,9: 868.https://doi.org/10.3389/fmicb.2018.00868.

喀斯特洞穴特境：

7.Li Tuo,Lin Guo,Shao-Wei Liu,Jia-Meng Liu,Yu-Qin Zhang,Zhong-Ke Jiang,Xian-Fu Liu,Li Chen,Jian Zu and Cheng-Hang Sun*: Lysinibacter cavernae gen.nov.,sp.nov.,a new member of the family Microbacteriaceae isolated from a karst cave.International Journal of Systematic and Evolutionary Microbiology,2015,65: 3305-3312.https://doi.org/10.1099/ijsem.0.000415.

8.Zhong-ke Jiang,Lin Guo,Chuan Chen,Shao-wei Liu,Lin Zhang,Su-juan Dai,Qi-yang He,Xue-fu You,Xinxin Hu,Li Tuo,Wei Jiang*and Cheng-Hang Sun*: Xiakemycin A,a novel pyranonaphthoquinone antibiotic,produced by the Streptomyces sp.CC8-201 from the soil of a karst cave.The Journal of Antibiotics,2015,68: 771-774.https://doi.org/10.1038/ja.2015.70.

9.Xiao-Jun Li,Su-Juan Dai,Shao-Wei Liu,Jia-Meng Liu,Li Chen,Lin Hu and Cheng-Hang Sun*:Tenggerimyces flavus sp.nov.,isolated from soil in a karst cave and emended description of the genus Tenggerimyces.International Journal of Systematic and Evolutionary Microbiology.2016,66: 1499-1505.https://doi.org/10.1099/ijsem.0.000908.

鹽湖特境：

10.Qin Yang,Pu-Yu Guo,Elena Y.Abidueva,Fei- Na Li,Chun- mei Xue,Shao- Wei Liu*,and Cheng-Hang Sun*: Hoyosella lacisalsi sp.nov.,a halotolerant actinobacterium isolated from Lake Gudzhirganskoe.Journal of Systematic and Evolutionary Microbiology.2021,71(12).https://doi.org/10.1099/ijsem.0.005145.

11.Xiao-Jun Li,Jia-Meng Liu,Yue Wu,Wei-Ming Zhang,Jing Li,Shao-Wei Liu,Gang Wu,Lin Hu,Li Chen,Da-Lin Huang,Rong-Feng Li and Cheng-Hang Sun*: Description of Salilacibacter albus gen.nov.,sp.nov.,isolated from a dried Salt Lake and reclassification of Paraglycomyces xinjiangensis Luo et al.2015 as a later heterotypic synonym of Salininema proteolyticum Nikou et al.2015 with emended descriptions of the genus Salininema and Salininema proteolyticum.International Journal of Systematic and Evolutionary Microbiology.2016,66: 2558-2565.https://doi.org/10.1099/ijsem.0.001093.

12.Lin Guo,Li Tuo,Xugela Habden,Yu-qin Zhang,Jia-meng Liu,Zhong-ke Jiang,Shao-wei Liu,Tohty Dilbar*and Cheng-hang Sun*: Allosalinactinospora lopnorensis gen.nov.,sp.nov.,a new member of the family Nocardiopsaceae isolated from soil.International Journal of Systematic and Evolutionary Microbiology,2015,65:206-213.https://doi.org/10.1099/ijs.0.055160-0.