摘要:目的 觀察中藥藥浴聯(lián)合NB-UVB(窄譜中波紫外線)治療尋常型銀屑病的療效。方法 將我院收治的84例尋常型銀屑病患者隨機(jī)分為兩組(每組42例),對(duì)照組應(yīng)用NB-UVB治療,觀察組采用NB-UVB、中藥藥浴聯(lián)合治療,對(duì)比兩組的療效。結(jié)果 觀察組的治療總有效率為95.2%,顯著高于對(duì)照組的76.2%,(P<0.05),差異有統(tǒng)計(jì)學(xué)意義;觀察組的住院時(shí)間及不良反應(yīng)發(fā)生率均顯著優(yōu)于對(duì)照組,(P<0.05)。結(jié)論 中藥藥浴聯(lián)合NB-UVB治療尋常型銀屑病具有顯著的療效,且不良反應(yīng)小,可有效加快患者康復(fù)進(jìn)程。
關(guān)鍵詞:中藥藥浴;NB-UVB;銀屑病;尋常型
Observe the Traditional Chinese Medicine Bath Combined with NB-UVB in the Treatment of Psoriasis Vulgaris
ZHOU Mei-lian,YIN Bao-hui
(Department of Dermatology,Dingzhou City People's Hospital,Dingzhou 073000,Hebei,China)
Abstract:Objective To observe the traditional Chinese medicine bath combined with NB-UVB efficacy in the treatment of psoriasis vulgaris. Methods To divide randomly 84 patients of psoriasis vulgaris in our hospital into 2 groups (each group 42 cases), the control group using NB-UVB treatment, observation group were treated with NB-UVB, traditional Chinese medicine medicated bath treatment, curative effect of two groups. Results The treatment the total effective rate of observation group was 95.2%, significantly higher than the control group (76.2%, P<0.05), the difference was statistically significant; in-hospital time of the observation group and adverse reaction rate was significantly better than the control group, (P<0.05). Conclusion The traditional Chinese medicine bath combined with NB-UVB therapy has significant curative effect of psoriasis vulgaris, and little adverse reaction, can effectively accelerate rehabilitation process.
Key words:Medicinal bath; NB-UVB; Psoriasis vulgaris
銀屑病是臨床常見(jiàn)的慢性炎癥性皮膚病,其具有易復(fù)發(fā)的特點(diǎn),臨床治療銀屑病的方法較多,然而在治療效果方面往往差強(qiáng)人意。我院在銀屑病的臨床治療中,采用了NB-UVB聯(lián)合中藥藥浴療法,獲得了理想的療效,報(bào)道如下。
1 資料與方法
1.1一般資料
2 結(jié)果
兩組患者的療效對(duì)比,見(jiàn)表1。觀察組的治療總有效率為95.2%,顯著高于對(duì)照組的76.2%,P<0.05,差異有統(tǒng)計(jì)學(xué)意義。
3 討論
目前,關(guān)于銀屑病的病因還沒(méi)有明確的解釋,大部分認(rèn)為其是多基因遺傳背景下T細(xì)胞街道的免疫性疾病。NB-UVB的波長(zhǎng)為311nm,具有極強(qiáng)的穿透性,可直達(dá)表皮深層通過(guò)生物學(xué)效應(yīng)誘導(dǎo)T淋巴細(xì)胞凋亡,從而達(dá)到治療目的。中藥藥浴方劑中所含的土槿皮、土茯苓、地膚子具有止癢、解毒、利濕、清熱之功效,白蘚皮、苦參、徐長(zhǎng)卿具有涼血解毒、清熱燥濕的功效,白蒺藜、當(dāng)歸具有補(bǔ)血、活血之功,大黃可瀉火清熱,諸藥合用可達(dá)到潤(rùn)膚止癢、養(yǎng)血活血、清熱解毒的功效[3]。……