
[摘要] 目的 探析布地奈德聯合鹽酸氨溴索霧化吸入治療小兒毛細支氣管炎的臨床療效。方法 方便選取該院2014年1月—2015年12月收治的90例小兒毛細支氣管炎患兒,隨機將其分為治療組和對照組,各45例,對照組給予鹽酸氨溴索霧化吸入,治療組在對照組基礎上聯合布地奈德霧化吸入,比較兩組治療效果及氣促、喘憋、哮鳴音等臨床癥狀、體征消失時間。結果 治療組總有效率88.89%與對照組66.67%比較差異有統計學意義,P<0.05;治療組氣喘消失時間(5.0±1.2)d、哮鳴音消失時間(3.0±0.3)d、濕啰音消失時間(7.3±1.2)d、住院時間(7.0±1.1)d,與對照組比較差異有統計學意義,P<0.05。結論 布地奈德聯合鹽酸氨溴索霧化吸入治療小兒毛細支氣管炎的臨床療效顯著,安全性很高,可快速緩解患者臨床癥狀,值得臨床推廣。
[關鍵詞] 布地奈德;鹽酸氨溴索;霧化吸入;毛細支氣管炎;臨床療效
[中圖分類號] R725 [文獻標識碼] A [文章編號] 1674-0742(2016)11(a)-0121-03
[Abstract] Objective Of budesonide inhalation of ambroxol the clinical efficacy of treatment of children with bronchiolitis.Methods Convenient selection our hospital in January 2014 - 90 cases of children with bronchiolitis were admitted in December 2015, were randomly divided into treatment group and control group of 45 patients in the control group were treated with ambroxol inhalation treatment group budesonide inhalation in the control group on the basis of clinical symptoms and therapeutic effects were compared shortness of breath, wheezing, wheezing and other signs disappeared time.Results Treatment group, the total efficiency of 88.89% compared with the control group, 66.67% significant difference, P <0.05; treated asthma disappeared time (5.0±1.2) d, wheeze disappeared time (3.0±0.3) d, auscultation disappearing time (7.3±1.2) d, length of stay(7.0±1.1) d, compared to the control group with significant difference,P <0.05.Conclusion The clinical efficacy of budesonide inhalation of ambroxol treatment of children with bronchiolitis was significantly high security, can quickly relieve the clinical symptoms, worthy of promotion.
[Key words] Budesonide; Ambroxol; Inhalation; Bronchiolitis; Clinical efficacy
小兒毛細支氣管炎是嬰幼兒時期常見的下呼吸道感染疾病,呼吸道合胞病毒為主要病原,常發生于2歲以下小兒,多數在6個月以內,常為首次發作。下呼吸道梗阻癥狀較為突出,表現為呼氣性呼吸困難、呼氣相延長伴喘憋,嚴重時可發生呼吸衰竭。至今對毛細支氣管炎仍無特效治療。為探析布地奈德聯合鹽酸氨溴索霧化吸入治療小兒毛細支氣管炎的臨床療效及可行性,該文將2014年1月—2015年12月收治的90例小兒毛細支氣管炎患兒,作為研究對象,現報道如下。
1 資料與方法
1.1 一般資料
方便選取該院收治的90例毛細支氣管炎患兒,年齡1月~2歲,入選病例符合毛細支氣管炎診斷標準[1],除外早產兒、免疫缺陷病、先天性心臟病、支氣管異物、肺結核、既往喘息病史等。……