
[摘要] 目的 探析C-反應蛋白(CRP)在小兒細菌性肺炎和支原體肺炎中的表達及臨床意義。方法 方便選取該院2013年1月—2015年12月收治的小兒細菌性肺炎(細菌性肺炎組)、支原體肺炎(支原體肺炎組)各30例,均在清晨抽取靜脈血測定血清C-反應蛋白水平,比較治療前后CRP水平。結果 細菌性肺炎組CRP水平治療前(44.02±14.35)mg/L,治療3 d后(15.83±6.32)mg/L,與支原體肺炎組(13.25±4.22)、(5.22±2.15)mg/L比較差異有統計學意義,P<0.05;細菌性肺炎組CRP治療前陽性率100%,治療3 d后陽性率53.33%與支原體肺炎組66.67%、20.00%比較差異有統計學意義,P<0.05。結論 小兒細菌性肺炎患兒CRP陽性率最高,給予CRP水平測定能夠更好的與支原體肺炎進行鑒別。
[關鍵詞] C-反應蛋白;小兒細菌性肺炎;支原體肺炎;臨床意義
[中圖分類號] R51 [文獻標識碼] A [文章編號] 1674-0742(2016)11(a)-0032-03
[Abstract] Objective Analysis of C- reactive protein (CRP) expression and clinical significance in children with bacterial pneumonia and mycoplasma pneumonia.Methods Convenient selection our hospital in January 2013 to December 2015 children admitted with bacterial pneumonia(bacterial pneumonia group), Mycoplasma pneumoniae(mycoplasma pneumonia group), 30 patients were in the early morning venous blood serum C-reactive protein levels, comparison of CRP levels before and after treatment.Results Former bacterial pneumonia group CRP levels treatment (44.02±14.35)mg/L, after 3 d treatment (15.83±6.32) mg/L, and mycoplasma pneumonia group (13.25±4.22)mg/L,(5.22±2.15) mg/L significant difference, P <0.05 was statistically significant; the positive rate of bacterial pneumonia group CRP before treatment to 100%, after treatment 3 d 53.33% positive rate of mycoplasma pneumonia group and 66.67%, 20.00% significant difference, P <0.05 was statistically significance.Conclusion Highest in children with bacterial pneumonia CRP positive rate, given CRP levels were measured to better identify and mycoplasma pneumonia.
[Key words] C- reactive protein; Children with bacterial pneumonia; Mycoplasma pneumoniae; Clinical Significance
CRP屬于急性時相反應蛋白,由機體肝臟產生。在正常的生理狀態下,機體內CRP的濃度非常低,當機體出現組織損傷或者出現炎癥時,CRP水平便會明顯升高,因此,CRP可用于區別病毒感染還是細菌感染[1]。為探析C-反應蛋白(CRP)在小兒細菌性肺炎和支原體肺炎中的表達及臨床意義,該文將該院2013年1月—2015年12月收治的小兒細菌性肺炎(細菌性肺炎組)、支原體肺炎(支原體肺炎組)各30例,作為該次研究對象,現報道如下。
1 資料與方法
1.1 一般資料
方便選取該院收治的小兒細菌性肺炎(細菌性肺炎組)、支原體肺炎(支原體肺炎組)各30例,細菌性肺炎的確診以X線胸片檢查機痰檢獲得,支原體肺炎的確診以聚合酶鏈反應行咽拭子DNA檢測獲得。細菌性肺炎組:男患兒17例,女患兒13例,年齡6個月~10歲,平均(5.5±3.0)歲;……