[摘要] 目的 探討卵巢透明細胞癌的MRI特點。 方法 回顧分析2010年7月—2015年6月間該院8例經病理證實為卵巢透明細胞癌患者的MRI圖像資料。 結果 8例病灶均為單側發病囊實性腫塊。1例形態不規則呈分葉狀,7例形態規則呈圓形或類圓形。8例病灶均可見包膜。3例為單房,其余5例均為多房,囊壁尚規則。腫塊囊性部分可合并出血,因出血時期不同,T1WI可呈高、中、低混雜信號,T2WI均呈高信號;實性部分表現為附壁軟組織灶,T1WI呈等信號,T2W呈稍高信號,DWI呈高信號,動態增強掃描實性部分動脈期不均勻強化,延遲期逐漸強化。6例腫塊可見同側增粗卵巢靜脈沿著腫瘤邊緣走行。3例合并對側附件子宮內膜樣囊腫。1例合并右下肢深靜脈血栓。 結論 卵巢透明細胞癌的MRI表現具有特征性,結合臨床資料,可提高術前診斷的正確率。
[關鍵詞] 卵巢惡性腫瘤,透明細胞癌,磁共振成像,診斷
[中圖分類號] R44 [文獻標識碼] A [文章編號] 1674-0742(2016)11(c)-0193-03
[Abstract] Objective To explore the MRI feature of ovarian clear cell carcinoma(OCCC). Methods Datum of 8 OCCC patients confirmed by pathology between July 2010 and June 2015 in our hospital were retrospectively analyzed. Results Tumors were unilateral , cystic and solid in all patients.1 case showed irregular lobulated shape, the next seven showed ovoid and round shape.8 tumors have visible capsule. 3 cases were single locular, 5 cases were muiltlocular, cystic wall were regular. cystic part of the tumor can be combined with hemorrhage, because of different bleeding times, T1WI showed hyperintense ,isointense, hypointense, T2WI all showed hyperintense. The tumors were with solid mural nodules, T1WI showed isointense, T2W and DWI showed hyperintense, and heterogeneous enhancement in arterial phase, obvious enhancement in delayed phase.6 cases showed that the ipsilateral thickening ovarian vein along the edge of the tumor. 3 cases associated with contralateral accessory endometrial cyst. 1 case associated with right lower extremity deep vein thrombosis. Conclusion MRI manifestation of OCCC have some characteristics, in combination with clinical data, can improve the preoperative diagnostic accuracy.
[Key words] Malignant tumor of ovary; Clear cell carcinoma; Magnetic resonance imaging; Diagnosis
卵巢透明細胞癌(ovarian clear cell carcinoma,OCCC) 起源于苗勒氏管,是由透明細胞、鞋釘樣細胞及嗜酸細胞組成的卵巢表面上皮-間質性惡性腫瘤[1],約占上皮來源卵巢惡性腫瘤的5%~11%。其早期患者相對較多,多見于圍絕經期婦女,臨床癥狀不典型,對常規以鉑類為主的化療方案敏感性、反應率低,預后不良。目前卵巢透明細胞癌MRI表現的國內報道相對較少,術前診斷正確率低。該文回顧2010年7月—2015年6月間8例病理證實的OCCC的MRI表現,分析其特征性,提高術前診斷的正確率。
1 資料與方法
1.1 一般資料
收集該院2010年7月—2015年6月間經病理證實的OCCC 8例,年齡33~72歲,中位年齡47歲。……