[摘要] 目的 探討原發性閉角型青光眼患者術后發生惡性青光眼的危險因素。方法 方便選取該院2012年6月—2015年12月收治的530例(664眼)原發性閉角型青光眼患者作為研究對象,根據術后是否發生惡性青光眼分為觀察組13例(19眼)和對照組517例(645眼),通過A/B超和UBM對患者前房深度、LOWE系數、眼軸長度、晶狀體厚度及術前眼壓等指標進行檢測,分析觀察指標與惡性青光眼發生的關聯性。結果 與對照組相比,觀察組患者眼軸(20.97±0.75)mm較短、晶狀體 (4.27±0.38)mm較薄、術前眼壓 (35.15±5.31)mmHg較高,差異有統計學意義(P<0.05);兩組前房深度和LOWE系數以及性別和手術方式上差異無統計學意義(P>0.05);在年齡、術前眼壓、眼軸長度(χ2=6.32)、前房深度及晶狀體厚度上差異有統計學意義(P<0.05)。結論 年齡較小、術前眼壓高、眼軸較短、前房厚度較淺及晶狀體較薄的原發性閉角型青光眼術后易發生惡性青光眼。
[關鍵詞] 原發性閉角型青光眼;危險因素;惡性青光眼
[中圖分類號] R776.1 [文獻標識碼] A [文章編號] 1674-0742(2016)11(c)-0099-03
[Abstract] Objective To explore the risk factors of malignant glaucoma occurrence after filtration surgery for primary glaucoma. Methods Convenient selection our hospital were treated 530 cases (664 eyes) of primary angle-closure glaucoma patients as research subjects in June 2012 - December 2015, according to the occurrence of malignant glaucoma after surgery is divided into observation group of 13 cases (19 eyes) and control group of 517 cases (645 eyes), A/B ultrasound and UBM were used to detect anterior chamber thickness、LOWE coefficient、axis length、lens thickness and preoperative IOP, correlation analysis observed indicators of malignant glaucoma. Results Compared with the control group, the observation group of patients with ocular axis (20.97 ± 0.75)mm, short lens (4.27 ± 0.38)mm thinner, preoperative intraocular pressure (35.15 ± 5.31)mmHg is higher, the difference was statistically significant (P < 0.05); two groups of anterior chamber depth and LOWE coefficient as well as the sex and type of surgery without statistical difference significance (P > 0.05); in the age, preoperative intraocular pressure and ocular axial length (χ2=6.32), there was statistical significance between anterior chamber depth and lens thickness (P < 0.05). Conclusion The patients with primary angle closure glaucoma were prone to malignant glaucoma after the operation of the primary angle closure glaucoma with small age, high intraocular pressure, short axial length, anterior thickness and thin lens.
[Key words] Primary angle-closure glaucoma; Risk factors; Malignant glaucoma
惡性青光眼(Malignant Glaucoma)又名睫狀環阻滯性閉角型青光眼,目前尚未明確該病發病機制[1-2]。原發性閉角型青光眼(PACG)是眼科常見的青光眼類型,其術后可發生惡性青光眼,對患者造成嚴重損害,預防惡性青光眼出現具有重要臨床意義。該文將該院2012年6月—2015年12月收治的530例(664眼)原發性閉角型青光眼患者作為研究對象,觀察患者術后是否出現惡性青光眼,分析研究發生惡性青光眼的危險因素,現報道如下。
1 資料與方法
1.1 一般資料
該文方便選取該院收治的530例(664眼)原發性閉角型青光眼患者作為研究對象,根據患者發病情況分為急性閉角型青光眼和慢性閉角型青光眼,其中男性220例,女性310例,年齡30~76歲,平均年齡(58.27±4.81)歲。……