對采用奧曲肽對患有急性水腫型胰腺炎疾病的患者實施治療的效果觀察

[摘要] 目的 針對奧曲肽對急性水腫型胰腺炎患者的治療效果進行評估。方法 隨機抽選2014年1月—2016年2月在該院接受救治的急性水腫型胰腺炎患者140例為研究對象，結(jié)合患者入院時間先后分為兩組。對照組（70例）患者均給予生長抑素酶抑制劑等常規(guī)西醫(yī)治療，觀察組（70例）患者則在此基礎上添加奧曲肽治療，評估兩組患者治療效果差異，同時統(tǒng)計患者腹痛消失時間、血象恢復時間、正常進食時間等指標，測定患者治療后體內(nèi)血淀粉酶水平以及血清C反應蛋白含量，統(tǒng)計患者不良反應發(fā)生率。結(jié)果 觀察組患者治療有效率（94.3%）明顯高于對照組（80.0%），差異有統(tǒng)計學意義（P<0.05）。觀察組患者治療后腹痛消失時間、血象恢復時間、恢復正常進食時間等均低于對照組，差異有統(tǒng)計學意義（P<0.05）。同時觀察組患者治療后血淀粉酶水平以及血清C反應蛋白含量明顯低于對照組，差異有統(tǒng)計學意義（P<0.05）。觀察組患者不良反應發(fā)生率（7.1%）低于對照組（21.4%），差異有統(tǒng)計學意義（P<0.05）。結(jié)論 常規(guī)西醫(yī)基礎上添加奧曲肽治療急性水腫型胰腺炎患者效果顯著，能促使患者癥狀更快緩解且優(yōu)化患者身體指標，同時安全性高，值得臨床推廣。

[關(guān)鍵詞] 奧曲肽；急性水腫型胰腺炎；癥狀緩解；生化指標；不良反應

[中圖分類號] R5 [文獻標識碼] A [文章編號] 1674-0742（2016）11（c）-0121-03

[Abstract] Objective In view of the octreotide in patients with acute edema type pancreatitis to evaluate therapeutic effect. Methods Random selected in January 2014 — February 2016 in our hospital treated 140 cases of patients with acute edema type pancreatitis as the research object， combined with patients hospitalized time has been divided into two groups. Control group（70 cases） patients were given somatostatin enzyme inhibitors such as conventional western medicine treatment， the observation group（70 cases） patients， on the basis of adding the peptide treatment， evaluation of two groups of patients with different treatment effects， and statistical recovery time of patients with abdominal pain disappear time， blood picture， normal eating time indicators， such as determination of blood amylase levels after treatment and the content of serum c-reactive protein， statistical patients incidence of adverse reactions. Results The observation group of patients treatment efficient （94.3%） is significantly higher than control group （80.0%）， there is statistical significance difference（P < 0.05）. Observation group after treatment in patients with abdominal pain disappear time， recovery time， back to normal eating urinalysis performed time are lower than the control group， significant difference （P< 0.05）. At the same time observation group of patients after treatment of blood amylase levels and serum c-reactive protein levels significantly lower than the control group， significant difference （P < 0.05）. Observation group of patients incidence of adverse reactions（7.1%） is lower than the control group （21.4%） and significant difference （P < 0.05）. Conclusion On the basis of conventional western medicine to add the effect of octreotide in treatment of acute edema type pancreatitis patients， can cause symptoms resolve faster and optimization patients body index， at the same time， high safety， worth clinical promotion.

[Key words] The octreotide； Acute edema type pancreatitis； Of symptoms； Biochemical indicator； Adverse reactions

急性水腫型胰腺炎是當前臨床較為常見的一種急腹癥類型，患者表現(xiàn)出明顯的上腹部疼痛癥狀，部分患者存在惡心、嘔吐等癥狀，病情嚴重者甚至直接休克死亡[1]。臨床實踐證實[2]，患者經(jīng)保守藥物治療即可治愈。……