[摘要] 目的 評價有創無創序貫機械通氣搶救重癥老年呼吸衰竭患者的有效性與安全性。方法 依據隨機分組的方式將方便選取2013年2月—2015年12月份該院收治的118例重癥老年呼吸衰竭患者隨機分為觀察組與對照組,觀察組采取有創無創序貫機械通氣治療,對照組實施持續有創機械通氣治療,將兩組治療效果與治療中患者應激反應情況作以對比分析。結果 觀察組PaO2、SaO2指標分別為(85.6±7.14)mmHg、(96.3±3.17)%明顯高于對照組,PaCO2為(42.2±7.15)mmHg低于對照組,差異有統計學意義(P<0.05)且E水平為(91.8±10.2)ng/mL低于對照組(P<0.05),差異有統計學意義(P<0.05)。 結論 有創無創序貫機械通氣治療重癥老年呼吸衰竭能快速有效改善患者臨床癥狀與體征表現,效果確切,安全可靠。
[關鍵詞] 有創無創序貫機械通氣;呼吸衰竭;有效性;安全性
[中圖分類號] R563.8 [文獻標識碼] A [文章編號] 1674-0742(2016)11(c)-0029-03
[Abstract] Objective To evaluate the efficacy and safety of noninvasive and invasive mechanical ventilation in the treatment of elderly patients with severe respiratory failure. Methods Convenient selection according to randomized manner in February 2013 to December 2015 118 cases of elderly patients with respiratory failure were randomly divided into observation group and control group, the observation group adopted sequential invasive noninvasive mechanical ventilation in the treatment of the control group, the implementation of continuous invasive mechanical ventilation in the treatment of patients, stress responses and treatment outcomes of the two groups for comparative analysis. Results The observation group PaO2 and SaO2 index respectively (85.6 ± 7.14)mmHg、(96.3 ± 3.17)%, significantly higher than the control group, PaCO2 (42.2 ± 7.15)mmHg lower than the control group, the difference was statistically significant (P<0.05) and E level (91.8 ± 10.2)ng/mL lower than that of the control group (P<0.05), there was statistical significant difference(P<0.05). Conclusion Invasive noninvasive sequential mechanical ventilation in the treatment of severe respiratory failure in elderly patients can quickly and effectively improve the clinical symptoms and signs, the effect is exact, safe and reliable.
[Key words] Invasive noninvasive sequential mechanical ventilation; Respiratory failure; Efficacy; Safety
臨床搶救呼吸衰竭患者的治療方法包括氣管切開、呼吸機輔助呼吸等常用方法,但長期行氣管插管通氣治療患者并發呼吸機相關肺炎的風險性大,不僅影響治療效果同時增加患者醫療費用。有創無創序貫機械通氣在呼吸衰竭治療中應用有效克服了這一缺陷,該文對該院2013年2月—2015年12月份收治的118例重癥老年呼吸衰竭患者應用有創無創序貫機械通氣治療取得理想療效,現報道如下。
1 資料與方法
1.1 研究資料
研究對象為方便選取入住該院接受治療的118例重癥老年呼吸衰竭患者,觀察組與對照組各59例,觀察組男32例,年齡27例,年齡68~84歲,平均年齡(76.4±3.8)歲;對照組男34例,女25例,年齡66~88歲,平均年齡(78.2±4.3)歲,23例重癥肺炎,兩組患者基本資料差異無統計學意義(P>0.05)。……