[摘要] 目的 分析腸易激綜合征患者的發病原因,觀察綜合療法的臨床應用價值。方法 方便選取2010年4月—2014年3月入住該院消化內科的腸易激綜合征患者260例,按隨機數字表法將其分成實驗組130例,對照組130例,對照組患者應用培菲康、莫沙必利治療,實驗組在對照組基礎上應用黛力新治療,并給予心理安慰及運動指導,比較兩組治療效果。結果 治療后實驗組癥狀程度評分、癥狀頻率評分、腸易激綜合征治療有效率分別為(1.53±0.42)分、(1.42±0.52)分、96.2%,均優于對照組的(2.86±0.51)分、(2.75±0.55)分、84.6%,組間差異具有統計學意義(P<0.05)。結論 心理、分泌功能異常、腸道功能異常均是腸易激綜合征的相關因素,綜合療法在腸易激綜合征患者中具有較高的應用價值,值得在臨床應用、推廣。
[關鍵詞] 消化內科;腸易激綜合征;發病原因;臨床治療對策
[中圖分類號] R574 [文獻標識碼] A [文章編號] 1674-0742(2016)11(c)-0049-03
[Abstract] Objective To analyze the causes of the patients with irritable bowel syndrome, and to observe the clinical application value of the comprehensive therapy. Methods Convenient select April 2010 to March 2014 admitted in our hospital, Department of Gastroenterology, the intestinal irritable bowel syndrome patients 260 cases, divided into experimental group (130 cases) according to the random number table method, control group (130 cases), control group were treated with probiotic Kang, mosapride treatment, experimental group in the control group on the basis of the application of Deanxit in the treatment of and give psychological comfort and exercise instruction, compared two groups of therapeutic effect. Results After treatment the symptom scores and the frequency of symptoms score, irritable bowel syndrome treatment efficiency respectively(1.53±0.42)points, (1.42±0.52)points, 96.2% were better than those of the control group (2.86±0.51)points, (2.75±0.55)points and 84.6%, the difference between the two groups is significant (P < 0.05). Conclusion Psychological, endocrine dysfunction, intestinal function abnormalities are related factors of syndrome of irritable bowel syndrome, comprehensive therapy in irritable bowel syndrome patients with high application value, it is worth in clinical application and promotion.
[Key words] Digestive medicine; Irritable bowel syndrome; Pathogenesis; Clinical treatment strategy
腸易激綜合征為非器質性腸道功能紊亂性疾病,在老年患者中比較常見,近年來,人們生活節奏加快,生活、工作壓力增大,腸易激綜合征發病率呈逐年上升趨勢,患者多存在腹痛、腹部持續不適癥狀,以上癥狀可持續存在,也可間歇發作[1]。單一藥物治療腸易激綜合征,效果欠滿意,該研究為2010年4月—2014年3月130例腸易激綜合征患者應用綜合療法治療,獲得了較佳的效果,現報道如下。
1 資料與方法
1.1 一般資料
方便收集該院消化內科收治的腸易激綜合征患者260例,將其分成實驗組130例,對照組130例,入選病例均經結腸鏡、大便常規、鋇劑灌腸及輔助實驗室檢查確診?!?br>