蘆笛+楊娜+任永變+李紅梅

【摘要】目的:探討β-HCG比值聯(lián)合子宮內(nèi)膜厚度對(duì)早期不明位置妊娠者異位妊娠的預(yù)測(cè)價(jià)值。方法:從我院2011年2月至2014年12月間產(chǎn)生的妊娠病例中隨機(jī)選擇151例,回顧分析孕婦的血清β-HCG比值以及子宮內(nèi)膜厚度檢測(cè)方法及結(jié)果,并比較應(yīng)用該種檢測(cè)方法診斷宮內(nèi)妊娠正常、妊娠異常以及異位妊娠孕婦的診斷符合率。結(jié)果:異位妊娠孕婦的血清β-HCG比值明顯低于宮內(nèi)妊娠正常孕婦,其差異具有統(tǒng)計(jì)學(xué)意義(P<0.05);異位妊娠孕婦子宮內(nèi)膜厚度小于宮內(nèi)妊娠正常孕婦,其差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。此外,妊娠異常孕婦的血清β -HCG比值以及子宮內(nèi)膜厚度值均小于宮內(nèi)妊娠正常孕婦,其差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。血清β-HCG比值聯(lián)合子宮內(nèi)膜厚度檢測(cè)的診斷符合率明顯高于單項(xiàng)血清β-HCG比值或子宮內(nèi)膜厚度檢測(cè),其差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。此外,血清β-HCG比值以及子宮內(nèi)膜厚度的診斷方法在異位妊娠檢查中的診斷符合率要高于妊娠正常及妊娠異常兩類,其差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論:聯(lián)合β-HCG比值和子宮內(nèi)膜厚度兩項(xiàng)指標(biāo)進(jìn)行判斷,能夠在早期不明位置妊娠者異位妊娠的檢測(cè)過(guò)程中發(fā)揮比較準(zhǔn)確的預(yù)測(cè)作用,具有較高的診斷價(jià)值;同時(shí)這兩項(xiàng)判斷指標(biāo)僅需聯(lián)用非侵入性檢測(cè)技術(shù)就能達(dá)到有效檢測(cè)的目的,是婦產(chǎn)科檢測(cè)中一種安全系數(shù)高、真實(shí)準(zhǔn)確、值得推廣的方法。
【關(guān)鍵詞】β-HCG比值;子宮內(nèi)膜厚度;早期不明位置;異位妊娠;預(yù)測(cè)
【Abstract】Objectives: To explore the predictive value ofβ-hCG ratio joint endometrial thickness for early ectopic pregnancy of unknown location. Methods: 151 pregnant women in our hospital from February 2011 to December 2014 were randomly selected, and the clinical examination and diagnosis methods and results were retrospectively analyzed, to compare the diagnostic accordance rate for normal pregnancy, abnormal pregnancy and ectopic pregnancy. Results: The serum beta HCG ratio of ectopic pregnant women was significantly lower than normal pregnant women, with statistically significant difference (P< 0.05). The endometrial thickness of ectopic pregnant women was significantly less than normal pregnant women, with statistically significant difference (P< 0.05). The beta HCG ratio and endometrial thickness of abnormal pregnant women were less than the normal pregnant women, with statistically significant difference (P< 0.05). The joint diagnosis accordance rate of serum beta HCG ratio and endometrial thickness was obviously higher than either alone, with statistically significant difference (P< 0.05). In addition, the joint diagnosis accordance rate of ectopic pregnancy was higher than normal pregnancy and abnormal pregnancy, with statistically significant difference (P< 0.05). Conclusion: Joint use of beta hCG ratio and endometrial thickness is of remarkable value in the prediction of early ectopic pregnancy of unknown location. Combined with non-invasive detection technology, it is an effective detection method with high safety and accuracy, which is worth promoting.
【Key words】Beta hCG ratio; Endometrial thickness; Early unknown location; Ectopic pregnancy; Prediction
【中圖分類號(hào)】R714.22【文獻(xiàn)標(biāo)志碼】A
早期不明位置妊娠一般指4~6周孕周的孕婦經(jīng)妊娠試驗(yàn)結(jié)果呈陽(yáng)性,但超聲檢查過(guò)程中并未發(fā)現(xiàn)有宮內(nèi)孕囊的一種情況,臨床醫(yī)學(xué)統(tǒng)計(jì)表明,該種情況的發(fā)生率8%以上[1]。異位妊娠作為產(chǎn)科中比較常見(jiàn)的急腹癥,是引起孕婦死亡的主要原因之一。由于異位妊娠的早期診斷缺乏相關(guān)的敏感性指標(biāo),異位妊娠常常被視為早期妊娠的高危并發(fā)癥。本文從我院2011年2月至2014年12月間產(chǎn)生的妊娠病例中隨機(jī)選擇151例,著重探討了β-hCG比值聯(lián)合子宮內(nèi)膜厚度對(duì)早期不明位置妊娠者異位妊娠的預(yù)測(cè)價(jià)值,得出的結(jié)果報(bào)道如下。endprint
1資料與方法
1.1基本資料
本次研究隨機(jī)選擇151例早期妊娠病例中的患者,均符合以下條件:經(jīng)過(guò)了妊娠試驗(yàn)或者血清檢測(cè),全部孕婦的妊娠試驗(yàn)結(jié)果顯示為陽(yáng)性,或者血清β-HCG的檢測(cè)值大于10U/L;停經(jīng)34~56d,平均停經(jīng)(40.3±0.5)d;TVS結(jié)果顯示未發(fā)現(xiàn)有宮內(nèi)孕囊,未顯示盆腔有明顯積血;……