周榮華+李青

【摘要】 目的 探析CO2點(diǎn)陣激光療法聯(lián)合果酸治療痤瘡后凹陷性瘢痕的效果。方法 200例痤瘡后凹陷性瘢痕患者, 隨機(jī)分為對(duì)照組和觀察組, 每組100例。對(duì)照組給予常規(guī)CO2點(diǎn)陣激光療法, 觀察組給予CO2點(diǎn)陣激光療法聯(lián)合果酸治療。對(duì)比兩組治療效果及不良反應(yīng)發(fā)生情況。結(jié)果 經(jīng)3個(gè)周期的治療, 觀察組患者治療總有效率為96.0%, 明顯高于對(duì)照組的88.0%(P<0.05)。觀察組患者不良反應(yīng)總發(fā)生率為6.0%, 低于對(duì)照組的15.0%(P<0.05)。結(jié)論 CO2點(diǎn)陣激光與果酸配合治療痤瘡后凹陷性瘢痕療效確切, 安全性高, 減輕患者治療期間的痛苦, 值得推廣。
【關(guān)鍵詞】 CO2點(diǎn)陣激光;果酸;痤瘡后凹陷性瘢痕;不良反應(yīng)
DOI:10.14163/j.cnki.11-5547/r.2018.01.055
【Abstract】 Objective To discuss and analyze the effect of fractional CO2 laser combined with fruit acid in the treatment of acne cicatricial scar after acne. Methods A total of 200 patients with acne cicatricial scar after acne were randomly divided into control group and observation group, with 100 cases in each group. The control group received conventional fractional CO2 laser, and the observation group received fractional CO2 laser combined with fruit acid. Comparison were made on treatment effect and occurrence of adverse reactions between two groups. Results After 3 cycles of treatment, the observation group had obviously higher total treatment effective rate as 96.0% than 88.0% in the control group (P<0.05). The observation group had lower incidence of total adverse reactions as 6.0% than 15.0% in the control group (P<0.05). Conclusion Combination of fractional CO2 laser and fruit acid provides affirmative efficacy in treating acne cicatricial scar after acne with high safety, and can relieve pain during treatment. It is worthy of promotion.
【Key words】 Fractional CO2 laser; Fruit acid; Acne cicatricial scar after acne; Adverse reactions
痤瘡是好發(fā)于青年人的皮膚病, 嚴(yán)重的患者在痤瘡愈合后常出現(xiàn)凹陷性瘢痕, 影響患者的面容美觀[1], 給患者的身心健康帶來(lái)不良影響。伴隨著美容醫(yī)學(xué)的發(fā)展, 在痤瘡后凹陷性瘢痕的治療中方法也越來(lái)越多, 但不少療法的效果不穩(wěn)定。近年來(lái)本院將CO2點(diǎn)陣激光與果酸結(jié)合治療, 取得滿意療效, 報(bào)告如下。
1 資料與方法
1. 1 一般資料 選取本院皮膚科2014年8月~2017年8月收治的200例痤瘡后凹陷性瘢痕患者, 隨機(jī)分為對(duì)照組和觀察組, 每組100例。對(duì)照組患者中男38例, 女62例;年齡25~54歲, 平均年齡(32.9±7.0)歲;病程7個(gè)月~4年, 平均病程(2.48±0.65)年;中度瘢痕73例, 重度瘢痕27例。觀察組患者中男41例, 女59例;年齡23~51歲, 平均年齡(32.5±
6.2)歲;病程9個(gè)月~4.5年, 平均病程(2.54±0.69)年;中度瘢痕75例, 重度瘢痕25例。兩組患者一般資料比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05), 具有可比性。
1. 2 方法 兩組患者均給予CO2點(diǎn)陣激光療法:做好術(shù)前準(zhǔn)備, 在患者需要激光的部位外敷利多卡因乳膏給予麻醉, 1 h
后擦除并使用消毒液消毒;根據(jù)瘢痕的深度、皮損等選擇波長(zhǎng)2600~3000 nm, 能量密度為20~30 J/cm2, 脈寬為8~12 ms, 頻率為200 Hz, 點(diǎn)間距為1~3 mm, 間隔時(shí)間為0.4~0.6 s。先……