地黃飲子治療老年性癡呆癥的臨床效果分析

汪慶華

[摘要] 目的 分析地黃飲子治療老年性癡呆癥的臨床效果。 方法 方便選擇2015年2月—2017年3月該院診治的76例老年性癡呆癥患者，根據隨機數字表分組，各38例。西醫治療組采用常規西藥多奈哌齊治療，地黃飲子組在西醫治療組基礎上給予地黃飲子治療。比較兩組老年性癡呆癥治療總有效率；藥物起效時間、藥物不良反應發生率；干預前后患者日常生活能力量表評分、簡易精神狀態評價量表評分、長谷川癡呆量表評分。結果 地黃飲子組老年性癡呆癥治療總有效率36（94.74%）高于西醫治療組30（78.95%）（P<0.05）；地黃飲子組藥物起效時間（6.51±1.41）d短于西醫治療組（8.39±2.13）d（P<0.05）；兩組患者藥物不良反應發生率相近，均為7.89%（P>0.05）；干預前兩組日常生活能力量表評分、簡易精神狀態評價量表評分、長谷川癡呆量表評分相近（P>0.05）；干預后地黃飲子組日常生活能力量表評分、簡易精神狀態評價量表評分、長谷川癡呆量表評分（90.35±3.95）分、（20.12±2.85）分、（15.35±2.95）分優于西醫治療組（78.01±4.55）分、（18.31±2.36）分、（13.01±1.55）分（P<0.05）。結論 地黃飲子治療老年性癡呆癥的臨床效果確切，可有效改善患者癡呆癥狀和認知功能，促進其日常生活能力的提高，無明顯不良反應，且起效快，值得推廣。

[關鍵詞] 地黃飲子；老年性癡呆癥；臨床效果

[中圖分類號] R4 [文獻標識碼] A [文章編號] 1674-0742（2017）12（a）-0177-03

[Abstract] Objective To analyze the clinical effect of dihuang drink in treatment of senile dementia. Methods 76 cases of senile dementia patients from February 2015 to March 2017 in this hospital were convenient selected and divided into two groups with 38 cases in each， the western medicine group adopted the routine western medicine donepezil， while the dihuang drink group were treated with dihuang drink on the basis of the western medicine group， and the total effective rate， drug onset time， incidence rate of drug adversereaction， daily living activity scale of patients before and after intervention， mini-mental state scale score and Kyohko Hasegawas dementia scale score of the two groups were compared. Results The total treatment effective rate in the dihuang drink group was higher than that in the western medicine group[36（94.74%） vs 30（78.95%）]（P<0.05）， and the drug onset time in the dihuang drink group was shorter than that in the western medicine group， [（6.51±1.41）d vs （8.39±2.13）d]（P<0.05）， and the incidence rate of drug adversereaction in the two groups was similar （7.89%）（P>0.05）， and the daily living activity scale score， mini-mental state score， and Kyohko Hasegawas dementia scale score in the dihuang drink group were better than those in the western medicine group[（90.35±3.95）points，（20.12±2.85）points，（15.35±2.95）points vs （78.01±4.55）points，（18.31±2.36）points，（13.01±1.55）points]（P<0.05）. Conclusion The clinical effect of dihuang drink in treatment of senile dementia is definite， which can effectively improve the dementia and cognition function， promote the improvement of daily living activities without obvious adversereaction and the onset is rapid， which is worth promotion.

[Key words] Dihuang drink； Senile dementia； Clinical effectendprint

老年性癡呆癥是一種常見神經性衰退疾病，也稱為阿爾茨海默病，患者以認知力和記憶力減退、大腦皮質等中樞神經功能退化、日常生活能力進行性減退等為主要特征，且伴隨思維、記憶、辨認、情緒等方面異常[1]。目前，隨著我國老齡化不斷發展，老年性癡呆癥已經成為繼心臟病、中風和腫瘤后第四大人類殺手之一，對患者身體健康、生命安全以及家庭帶來了嚴重影響。該研究方便選擇2015年2月—2017年3月該院收治的76例老年性癡呆癥患者，根據隨機數字表分組，各38例，探討了地黃飲子治療老年性癡呆癥的臨床效果，現報道如下。